Duration of ECMO is an independent predictor of intracranial hemorrhage occurring during ECMO support

Hesham R. Omar, Mehdi Mirsaeidi, Devanand Mangar, Enrico M. Camporesi

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

We assessed the incidence and predictors of intracranial hemorrhage (ICH) occurring during ECMO support. Out of 154 patients who received ECMO, 12 (7.8%) developed ICH. Patients with ICH had a longer ECMO duration (10.3 vs. 5.3days, P=0.029), higher activated clotting time (ACT,P=0.027), higher frequency of central ECMO cannulation (P=0.039) and a trend towards higher in-hospital mortality(92% vs. 65%,P=0.091). Multivariate analysis showed that a longer ECMO duration(OR=1.079,95%CI=1.012-1.150,P=0.020) and central ECMO cannulation (OR=5.177,95%CI=1.325-20.220,P=0.018) are independently associated with risk of ICH. We recommend routine neurological checks, monitoring of coagulation parameters and to attempt earlier rather than late weaning from ECMO whenever feasible.

Original languageEnglish (US)
JournalASAIO Journal
DOIs
StateAccepted/In press - Mar 14 2016

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Intracranial Hemorrhages
Coagulation
Monitoring
Catheterization
Hospital Mortality
Weaning
Multivariate Analysis
Incidence

ASJC Scopus subject areas

  • Biophysics
  • Biomaterials
  • Bioengineering
  • Biomedical Engineering
  • Medicine(all)

Cite this

Duration of ECMO is an independent predictor of intracranial hemorrhage occurring during ECMO support. / Omar, Hesham R.; Mirsaeidi, Mehdi; Mangar, Devanand; Camporesi, Enrico M.

In: ASAIO Journal, 14.03.2016.

Research output: Contribution to journalArticle

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