Duration of ECMO is an independent predictor of intracranial hemorrhage occurring during ECMO support

Hesham R. Omar, Mehdi Mirsaeidi, Devanand Mangar, Enrico M. Camporesi

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

We assessed the incidence and predictors of intracranial hemorrhage (ICH) occurring during ECMO support. Out of 154 patients who received ECMO, 12 (7.8%) developed ICH. Patients with ICH had a longer ECMO duration (10.3 vs. 5.3days, P=0.029), higher activated clotting time (ACT,P=0.027), higher frequency of central ECMO cannulation (P=0.039) and a trend towards higher in-hospital mortality(92% vs. 65%,P=0.091). Multivariate analysis showed that a longer ECMO duration(OR=1.079,95%CI=1.012-1.150,P=0.020) and central ECMO cannulation (OR=5.177,95%CI=1.325-20.220,P=0.018) are independently associated with risk of ICH. We recommend routine neurological checks, monitoring of coagulation parameters and to attempt earlier rather than late weaning from ECMO whenever feasible.

Original languageEnglish (US)
JournalASAIO Journal
DOIs
StateAccepted/In press - Mar 14 2016

ASJC Scopus subject areas

  • Biophysics
  • Biomaterials
  • Bioengineering
  • Biomedical Engineering
  • Medicine(all)

Fingerprint Dive into the research topics of 'Duration of ECMO is an independent predictor of intracranial hemorrhage occurring during ECMO support'. Together they form a unique fingerprint.

Cite this