Drusen of the optic disc.

Byron L Lam, Christopher G. Morais, Joshua Pasol

Research output: Contribution to journalArticle

66 Citations (Scopus)

Abstract

Optic disc drusen are acellular calcific deposits occurring in small, crowded optic discs with abnormal vasculature. Evidence suggests axoplasmic transport alteration and axonal degeneration are involved in disc drusen formation. In affected patients, the number and size of disc drusen are highly variable, and the drusen may be visible near the disc surface or buried within the disc, causing them to appear as pseudopapilledema. B-scan echography is the most sensitive method for detecting disc drusen. Most patients with disc drusen are asymptomatic, but progressive visual field loss and vascular complications, including anterior ischemic optic neuropathy and choroidal neovascularization, may occur. Optic disc drusen have no established effective treatment. Diagnosing disc drusen correctly is important to avoid unnecessary work-up and to avoid overlooking potential serious conditions such as true papilledema. Disc drusen patients with more-than-expected visual field defects or progressive visual loss should have work-up to exclude other causes.

Original languageEnglish
Pages (from-to)404-408
Number of pages5
JournalCurrent Neurology and Neuroscience Reports
Volume8
Issue number5
DOIs
StatePublished - Sep 1 2008

Fingerprint

Optic Disk Drusen
Visual Fields
Ischemic Optic Neuropathy
Choroidal Neovascularization
Papilledema
Axonal Transport
Optic Disk
Blood Vessels
Ultrasonography
Therapeutics

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Drusen of the optic disc. / Lam, Byron L; Morais, Christopher G.; Pasol, Joshua.

In: Current Neurology and Neuroscience Reports, Vol. 8, No. 5, 01.09.2008, p. 404-408.

Research output: Contribution to journalArticle

Lam, Byron L ; Morais, Christopher G. ; Pasol, Joshua. / Drusen of the optic disc. In: Current Neurology and Neuroscience Reports. 2008 ; Vol. 8, No. 5. pp. 404-408.
@article{c2e04e5ad54b456e997e3c23b202c6d9,
title = "Drusen of the optic disc.",
abstract = "Optic disc drusen are acellular calcific deposits occurring in small, crowded optic discs with abnormal vasculature. Evidence suggests axoplasmic transport alteration and axonal degeneration are involved in disc drusen formation. In affected patients, the number and size of disc drusen are highly variable, and the drusen may be visible near the disc surface or buried within the disc, causing them to appear as pseudopapilledema. B-scan echography is the most sensitive method for detecting disc drusen. Most patients with disc drusen are asymptomatic, but progressive visual field loss and vascular complications, including anterior ischemic optic neuropathy and choroidal neovascularization, may occur. Optic disc drusen have no established effective treatment. Diagnosing disc drusen correctly is important to avoid unnecessary work-up and to avoid overlooking potential serious conditions such as true papilledema. Disc drusen patients with more-than-expected visual field defects or progressive visual loss should have work-up to exclude other causes.",
author = "Lam, {Byron L} and Morais, {Christopher G.} and Joshua Pasol",
year = "2008",
month = "9",
day = "1",
doi = "10.1007/s11910-008-0062-6",
language = "English",
volume = "8",
pages = "404--408",
journal = "Current Neurology and Neuroscience Reports",
issn = "1528-4042",
publisher = "Current Medicine Group",
number = "5",

}

TY - JOUR

T1 - Drusen of the optic disc.

AU - Lam, Byron L

AU - Morais, Christopher G.

AU - Pasol, Joshua

PY - 2008/9/1

Y1 - 2008/9/1

N2 - Optic disc drusen are acellular calcific deposits occurring in small, crowded optic discs with abnormal vasculature. Evidence suggests axoplasmic transport alteration and axonal degeneration are involved in disc drusen formation. In affected patients, the number and size of disc drusen are highly variable, and the drusen may be visible near the disc surface or buried within the disc, causing them to appear as pseudopapilledema. B-scan echography is the most sensitive method for detecting disc drusen. Most patients with disc drusen are asymptomatic, but progressive visual field loss and vascular complications, including anterior ischemic optic neuropathy and choroidal neovascularization, may occur. Optic disc drusen have no established effective treatment. Diagnosing disc drusen correctly is important to avoid unnecessary work-up and to avoid overlooking potential serious conditions such as true papilledema. Disc drusen patients with more-than-expected visual field defects or progressive visual loss should have work-up to exclude other causes.

AB - Optic disc drusen are acellular calcific deposits occurring in small, crowded optic discs with abnormal vasculature. Evidence suggests axoplasmic transport alteration and axonal degeneration are involved in disc drusen formation. In affected patients, the number and size of disc drusen are highly variable, and the drusen may be visible near the disc surface or buried within the disc, causing them to appear as pseudopapilledema. B-scan echography is the most sensitive method for detecting disc drusen. Most patients with disc drusen are asymptomatic, but progressive visual field loss and vascular complications, including anterior ischemic optic neuropathy and choroidal neovascularization, may occur. Optic disc drusen have no established effective treatment. Diagnosing disc drusen correctly is important to avoid unnecessary work-up and to avoid overlooking potential serious conditions such as true papilledema. Disc drusen patients with more-than-expected visual field defects or progressive visual loss should have work-up to exclude other causes.

UR - http://www.scopus.com/inward/record.url?scp=54049112736&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=54049112736&partnerID=8YFLogxK

U2 - 10.1007/s11910-008-0062-6

DO - 10.1007/s11910-008-0062-6

M3 - Article

C2 - 18713576

AN - SCOPUS:54049112736

VL - 8

SP - 404

EP - 408

JO - Current Neurology and Neuroscience Reports

JF - Current Neurology and Neuroscience Reports

SN - 1528-4042

IS - 5

ER -