“Double carbapenem” and oral fosfomycin for the treatment of complicated urinary tract infections caused by blaNDM-harboring Enterobacteriaceae in kidney transplantation

Rossana Rosa, Susan D. Rudin, Laura J. Rojas, Andrea M. Hujer, Armando Perez-Cardona, Federico Perez, Robert A. Bonomo, Octavio Martinez, Lilian M. Abbo, Jose F. Camargo

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Infections with carbapenemase-producing carbapenem-resistant Enterobacteriaceae represent an emergent problem worldwide. Treatment of infections caused by New Delhi metallo-beta-lactamase (NDM)-harboring Enterobacteriaceae is particularly challenging as it frequently involves the use of nephrotoxic agents, which is problematic in kidney transplant recipients and non-renal transplant patients with marginal kidney function. We present two cases of urinary tract infections caused by NDM-harboring Enterobacteriaceae successfully treated with a combination of “double carbapenem” and oral fosfomycin.

Original languageEnglish (US)
Article numbere12795
JournalTransplant Infectious Disease
Volume20
Issue number1
DOIs
StatePublished - Feb 1 2018

Keywords

  • NDM
  • carbapenem-resistant Enterobacteriaceae
  • carbapenemase
  • fosfomycin
  • kidney transplant

ASJC Scopus subject areas

  • Infectious Diseases
  • Transplantation

Fingerprint Dive into the research topics of '“Double carbapenem” and oral fosfomycin for the treatment of complicated urinary tract infections caused by bla<sub>NDM</sub>-harboring Enterobacteriaceae in kidney transplantation'. Together they form a unique fingerprint.

Cite this