Double-blind, placebo-controlled study assessing the effect of chocolate consumption in subjects with a history of acne vulgaris

Caroline Caperton, Samantha Block, Martha Viera, Jonette Keri, Brian Berman

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Objective: To assess the effect of chocolate on acne exacerbation in males between the ages of 18 and 35 with a history of acne vulgaris. Design: Double-blind, placebo-controlled, randomized, controlled trial. Setting: Single-site, outpatient, research, clinical facility at an academic research institution. Participants: Fourteen men between the ages of 18 and 35 were assigned to swallow capsules filled with either unsweetened 100-percent cocoa, hydrolyzed gelatin powder, or a combination of the two, at baseline. Measurements: Lesions were assessed and photographs were taken at baseline, Day 4, and Day 7. Results: Of the 14 subjects, 13 completed this Institutional Review Board approved study. A statistically significant increase in the mean number of total acneiform lesions (comedones, papules, pustules, nodules) was detected on both Day 4 (p=0.006) and Day 7 (p=0.043) compared to baseline. A small-strength positive Pearson's correlation coefficient existed between the amount of chocolate each subject consumed and the number of lesions each subject developed between baseline and Day 4 (r=0.250), while a medium-strength positive correlation existed between baseline and Day 7 (r=0.314). No serious adverse events occurred. Conclusion: It appears that in acne-prone, male individuals, the consumption of chocolate correlates to an increase in the exacerbation of acne.

Original languageEnglish
Pages (from-to)19-23
Number of pages5
JournalJournal of Clinical and Aesthetic Dermatology
Volume7
Issue number5
StatePublished - Jan 1 2014

Fingerprint

Acne Vulgaris
Placebos
Research Ethics Committees
Gelatin
Deglutition
Research
Powders
Capsules
Outpatients
Randomized Controlled Trials
Chocolate

ASJC Scopus subject areas

  • Dermatology

Cite this

Double-blind, placebo-controlled study assessing the effect of chocolate consumption in subjects with a history of acne vulgaris. / Caperton, Caroline; Block, Samantha; Viera, Martha; Keri, Jonette; Berman, Brian.

In: Journal of Clinical and Aesthetic Dermatology, Vol. 7, No. 5, 01.01.2014, p. 19-23.

Research output: Contribution to journalArticle

@article{7f1760db78b7418fb078592b2d1f6745,
title = "Double-blind, placebo-controlled study assessing the effect of chocolate consumption in subjects with a history of acne vulgaris",
abstract = "Objective: To assess the effect of chocolate on acne exacerbation in males between the ages of 18 and 35 with a history of acne vulgaris. Design: Double-blind, placebo-controlled, randomized, controlled trial. Setting: Single-site, outpatient, research, clinical facility at an academic research institution. Participants: Fourteen men between the ages of 18 and 35 were assigned to swallow capsules filled with either unsweetened 100-percent cocoa, hydrolyzed gelatin powder, or a combination of the two, at baseline. Measurements: Lesions were assessed and photographs were taken at baseline, Day 4, and Day 7. Results: Of the 14 subjects, 13 completed this Institutional Review Board approved study. A statistically significant increase in the mean number of total acneiform lesions (comedones, papules, pustules, nodules) was detected on both Day 4 (p=0.006) and Day 7 (p=0.043) compared to baseline. A small-strength positive Pearson's correlation coefficient existed between the amount of chocolate each subject consumed and the number of lesions each subject developed between baseline and Day 4 (r=0.250), while a medium-strength positive correlation existed between baseline and Day 7 (r=0.314). No serious adverse events occurred. Conclusion: It appears that in acne-prone, male individuals, the consumption of chocolate correlates to an increase in the exacerbation of acne.",
author = "Caroline Caperton and Samantha Block and Martha Viera and Jonette Keri and Brian Berman",
year = "2014",
month = "1",
day = "1",
language = "English",
volume = "7",
pages = "19--23",
journal = "Journal of Clinical and Aesthetic Dermatology",
issn = "1941-2789",
publisher = "Matrix Medical Communications",
number = "5",

}

TY - JOUR

T1 - Double-blind, placebo-controlled study assessing the effect of chocolate consumption in subjects with a history of acne vulgaris

AU - Caperton, Caroline

AU - Block, Samantha

AU - Viera, Martha

AU - Keri, Jonette

AU - Berman, Brian

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Objective: To assess the effect of chocolate on acne exacerbation in males between the ages of 18 and 35 with a history of acne vulgaris. Design: Double-blind, placebo-controlled, randomized, controlled trial. Setting: Single-site, outpatient, research, clinical facility at an academic research institution. Participants: Fourteen men between the ages of 18 and 35 were assigned to swallow capsules filled with either unsweetened 100-percent cocoa, hydrolyzed gelatin powder, or a combination of the two, at baseline. Measurements: Lesions were assessed and photographs were taken at baseline, Day 4, and Day 7. Results: Of the 14 subjects, 13 completed this Institutional Review Board approved study. A statistically significant increase in the mean number of total acneiform lesions (comedones, papules, pustules, nodules) was detected on both Day 4 (p=0.006) and Day 7 (p=0.043) compared to baseline. A small-strength positive Pearson's correlation coefficient existed between the amount of chocolate each subject consumed and the number of lesions each subject developed between baseline and Day 4 (r=0.250), while a medium-strength positive correlation existed between baseline and Day 7 (r=0.314). No serious adverse events occurred. Conclusion: It appears that in acne-prone, male individuals, the consumption of chocolate correlates to an increase in the exacerbation of acne.

AB - Objective: To assess the effect of chocolate on acne exacerbation in males between the ages of 18 and 35 with a history of acne vulgaris. Design: Double-blind, placebo-controlled, randomized, controlled trial. Setting: Single-site, outpatient, research, clinical facility at an academic research institution. Participants: Fourteen men between the ages of 18 and 35 were assigned to swallow capsules filled with either unsweetened 100-percent cocoa, hydrolyzed gelatin powder, or a combination of the two, at baseline. Measurements: Lesions were assessed and photographs were taken at baseline, Day 4, and Day 7. Results: Of the 14 subjects, 13 completed this Institutional Review Board approved study. A statistically significant increase in the mean number of total acneiform lesions (comedones, papules, pustules, nodules) was detected on both Day 4 (p=0.006) and Day 7 (p=0.043) compared to baseline. A small-strength positive Pearson's correlation coefficient existed between the amount of chocolate each subject consumed and the number of lesions each subject developed between baseline and Day 4 (r=0.250), while a medium-strength positive correlation existed between baseline and Day 7 (r=0.314). No serious adverse events occurred. Conclusion: It appears that in acne-prone, male individuals, the consumption of chocolate correlates to an increase in the exacerbation of acne.

UR - http://www.scopus.com/inward/record.url?scp=84901062151&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84901062151&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:84901062151

VL - 7

SP - 19

EP - 23

JO - Journal of Clinical and Aesthetic Dermatology

JF - Journal of Clinical and Aesthetic Dermatology

SN - 1941-2789

IS - 5

ER -