Donor-site morbidity after free ileocolon flap transfer for esophageal and voice reconstruction

Antonio Rampazzo, Christopher J. Salgado, Bahar Bassiri Gharb, Samir Mardini, Stefano Spanio Di Spilimbergo, Hung Chi Chen

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


BACKGROUND: Radical excision of advanced hypopharyngeal and laryngeal tumors usually compromises both swallowing and speech. Among the available reconstruction methods, the free ileocolon flap allows rehabilitation of both functions in one stage. The donor-site morbidity of this flap has not been addressed in head and neck cancer patients. METHODS: A retrospective study was conducted in 34 patients between April of 2003 and December of 2007 to investigate donor-site morbidity in patients undergoing reconstruction with free ileocolon flaps. Complications such as diarrhea, upper gastrointestinal tract distress, bowel leak, abscess, or hernia formation were evaluated. Significant association of diarrhea and upper gastrointestinal distress, previous abdominal operations, systemic diseases, primary versus secondary reconstruction, flap length, and postoperative chemotherapy were subsequently evaluated. Differences were considered significant for values of p ≤ 0.05. RESULTS: There were no perioperative or postoperative deaths. Nineteen patients (56 percent) experienced temporary diarrhea. In all but two patients, diarrhea discontinued by 4 months. Chemotherapy was significantly associated with diarrhea (p < 0.01). Colchicine, terbinafine, and heroin withdrawal episodically caused diarrhea but statistical conclusions could not be drawn. Six patients (18 percent) suffered from upper gastrointestinal tract problems (gastroduodenal ulcer, erosive gastritis, and minor bleeding), probably because of insufficient gastric protection. CONCLUSIONS: The free ileocolon flap proved to be a reliable method when simultaneous restoration of swallowing and speech was required, with donor-site morbidity comparable to that of the other intestinal flaps.

Original languageEnglish (US)
Pages (from-to)186e-194e
JournalPlastic and reconstructive surgery
Issue number6
StatePublished - Dec 2008
Externally publishedYes

ASJC Scopus subject areas

  • Surgery


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