Does the HIV-1deltakURNe vaccine strain hold the key to curbing HIV infection? An interview with Ronald Desrosiers, PhD.

R. Desrosiers

Does the HIV-1deltakURNe vaccine strain hold the key to curbing HIV infection? An interview with Ronald Desrosiers, PhD.

Research output: Contribution to journal › Article › peer-review

Abstract

Dr. Ronald Desrosiers of the New England Primate Research Center at the Harvard Medical School provides his opinions on the HIV-1deltakURNe vaccine strain. Dr. Desrosiers explains what this strain represents and how it was chosen for live-attenuated HIV vaccine human safety trials. Further, Desrosiers discusses the balance in using highly attenuated vaccines and protection effectiveness, whether it is possible for the vaccine strain to revert to a disease-causing form, the possibility of transmission of a vaccine virus to unvaccinated individuals, and the issue of cancer development through insertional mutagenesis.

Original language	English (US)
Pages (from-to)	45-46
Number of pages	2
Journal	Journal of the International Association of Physicians in AIDS Care
Volume	4
Issue number	3
State	Published - Mar 1998
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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abstract = "Dr. Ronald Desrosiers of the New England Primate Research Center at the Harvard Medical School provides his opinions on the HIV-1deltakURNe vaccine strain. Dr. Desrosiers explains what this strain represents and how it was chosen for live-attenuated HIV vaccine human safety trials. Further, Desrosiers discusses the balance in using highly attenuated vaccines and protection effectiveness, whether it is possible for the vaccine strain to revert to a disease-causing form, the possibility of transmission of a vaccine virus to unvaccinated individuals, and the issue of cancer development through insertional mutagenesis.",

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