TY - JOUR
T1 - Do selection criteria for children with dilated cardiomyopathy enrolled in national registries explain differences in outcomes?
AU - Weintraub, Robert G.
AU - Everitt, Melanie D.
AU - Alexander, Peta M.A.
AU - Wilkinson, James D.
AU - Lipshultz, Steven E.
PY - 2014/12/1
Y1 - 2014/12/1
N2 - Multi-center studies are necessary to examine the clinical course of childhood cardiomyopathy due to the heterogeneous nature and relatively low prevalence of the disease. Outcomes vary widely and are difficult to predict based on diagnosis, etiology, and presentation. Results from two national studies have enhanced our understanding of the epidemiology and natural history of childhood DCM but differences in outcome exist between these large cohorts. Herein, we summarize these differences with respect to cardiac recovery and transplant-free survival. The potential impact of differences in study design and cohort selection is highlighted.
AB - Multi-center studies are necessary to examine the clinical course of childhood cardiomyopathy due to the heterogeneous nature and relatively low prevalence of the disease. Outcomes vary widely and are difficult to predict based on diagnosis, etiology, and presentation. Results from two national studies have enhanced our understanding of the epidemiology and natural history of childhood DCM but differences in outcome exist between these large cohorts. Herein, we summarize these differences with respect to cardiac recovery and transplant-free survival. The potential impact of differences in study design and cohort selection is highlighted.
KW - Congestive heart failure
KW - Dilated cardiomyopathy
KW - Myocardial recovery
KW - Pediatrics
UR - http://www.scopus.com/inward/record.url?scp=84914115397&partnerID=8YFLogxK
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U2 - 10.1016/j.ppedcard.2014.10.005
DO - 10.1016/j.ppedcard.2014.10.005
M3 - Review article
AN - SCOPUS:84914115397
VL - 37
SP - 47
EP - 48
JO - Progress in Pediatric Cardiology
JF - Progress in Pediatric Cardiology
SN - 1058-9813
IS - 1-2
ER -