Do brainstem cavernous malformations have a higher rate of hemorrhage?

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


The natural history of brainstem cavernous malformation is particularly complex. Currently, there is a wide range of reported annual rates of hemorrhage. Many studies report a significantly higher rate of hemorrhage and/or rehemorrhage in cavernous malformations located in the brainstem, but this is quite controversial. It is possible that brainstem cavernous malformations have a higher risk of hemorrhage and rehemorrhage, but reported variance in the literature may also be due to study limitations along with selection, patient and disease-specific; follow-up; and recall bias. An accurate assessment of hemorrhagic risk along with evaluation of patient and lesion-specific characteristics is critical in the decision-making process for potential intervention, as microsurgical intervention can significantly decrease the risk of future hemorrhage, but may be associated with significant complications.

Original languageEnglish (US)
Pages (from-to)1109-1111
Number of pages3
JournalExpert review of neurotherapeutics
Issue number10
StatePublished - Oct 3 2015
Externally publishedYes


  • angioma
  • brainstem
  • cavernous
  • cavernous malformation
  • cerebral
  • hemangiomas
  • hemorrhage
  • intracranial
  • natural history
  • neurosurgery
  • surgery

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology
  • Pharmacology (medical)


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