Diverticular disease of the colon

Neil Stollman, Jeffrey Raskin

Research output: Contribution to journalArticle

409 Citations (Scopus)

Abstract

Colonic diverticulosis refers to small outpouchings from the colonic lumen due to mucosal herniation through the colonic wall at sites of vascular perforation. Abnormal colonic motility and inadequate intake of dietary fibre have been implicated in its pathogenesis. This acquired abnormality is typically found in developed countries, and its prevalence rises with age. Most patients affected will remain entirely asymptomatic; however, 10-20% of those affected can manifest clinical syndromes, mainly diverticulitis and diverticular haemorrhage. As our elderly population grows, we can anticipate a concomitant rise in the number of patients with diverticular disease. Here, we review the incidence, pathophysiology, clinical presentation, and management of diverticular disease of the colon and its complications.

Original languageEnglish
Pages (from-to)631-639
Number of pages9
JournalLancet
Volume363
Issue number9409
DOIs
StatePublished - Feb 21 2004

Fingerprint

Colon
Colonic Diverticulosis
Diverticulitis
Dietary Fiber
Disease Management
Developed Countries
Blood Vessels
Hemorrhage
Incidence
Population

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Stollman, N., & Raskin, J. (2004). Diverticular disease of the colon. Lancet, 363(9409), 631-639. https://doi.org/10.1016/S0140-6736(04)15597-9

Diverticular disease of the colon. / Stollman, Neil; Raskin, Jeffrey.

In: Lancet, Vol. 363, No. 9409, 21.02.2004, p. 631-639.

Research output: Contribution to journalArticle

Stollman, N & Raskin, J 2004, 'Diverticular disease of the colon', Lancet, vol. 363, no. 9409, pp. 631-639. https://doi.org/10.1016/S0140-6736(04)15597-9
Stollman N, Raskin J. Diverticular disease of the colon. Lancet. 2004 Feb 21;363(9409):631-639. https://doi.org/10.1016/S0140-6736(04)15597-9
Stollman, Neil ; Raskin, Jeffrey. / Diverticular disease of the colon. In: Lancet. 2004 ; Vol. 363, No. 9409. pp. 631-639.
@article{d839874459ec404baf5ca761ba2abca9,
title = "Diverticular disease of the colon",
abstract = "Colonic diverticulosis refers to small outpouchings from the colonic lumen due to mucosal herniation through the colonic wall at sites of vascular perforation. Abnormal colonic motility and inadequate intake of dietary fibre have been implicated in its pathogenesis. This acquired abnormality is typically found in developed countries, and its prevalence rises with age. Most patients affected will remain entirely asymptomatic; however, 10-20{\%} of those affected can manifest clinical syndromes, mainly diverticulitis and diverticular haemorrhage. As our elderly population grows, we can anticipate a concomitant rise in the number of patients with diverticular disease. Here, we review the incidence, pathophysiology, clinical presentation, and management of diverticular disease of the colon and its complications.",
author = "Neil Stollman and Jeffrey Raskin",
year = "2004",
month = "2",
day = "21",
doi = "10.1016/S0140-6736(04)15597-9",
language = "English",
volume = "363",
pages = "631--639",
journal = "The Lancet",
issn = "0140-6736",
publisher = "Elsevier Limited",
number = "9409",

}

TY - JOUR

T1 - Diverticular disease of the colon

AU - Stollman, Neil

AU - Raskin, Jeffrey

PY - 2004/2/21

Y1 - 2004/2/21

N2 - Colonic diverticulosis refers to small outpouchings from the colonic lumen due to mucosal herniation through the colonic wall at sites of vascular perforation. Abnormal colonic motility and inadequate intake of dietary fibre have been implicated in its pathogenesis. This acquired abnormality is typically found in developed countries, and its prevalence rises with age. Most patients affected will remain entirely asymptomatic; however, 10-20% of those affected can manifest clinical syndromes, mainly diverticulitis and diverticular haemorrhage. As our elderly population grows, we can anticipate a concomitant rise in the number of patients with diverticular disease. Here, we review the incidence, pathophysiology, clinical presentation, and management of diverticular disease of the colon and its complications.

AB - Colonic diverticulosis refers to small outpouchings from the colonic lumen due to mucosal herniation through the colonic wall at sites of vascular perforation. Abnormal colonic motility and inadequate intake of dietary fibre have been implicated in its pathogenesis. This acquired abnormality is typically found in developed countries, and its prevalence rises with age. Most patients affected will remain entirely asymptomatic; however, 10-20% of those affected can manifest clinical syndromes, mainly diverticulitis and diverticular haemorrhage. As our elderly population grows, we can anticipate a concomitant rise in the number of patients with diverticular disease. Here, we review the incidence, pathophysiology, clinical presentation, and management of diverticular disease of the colon and its complications.

UR - http://www.scopus.com/inward/record.url?scp=1342308177&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=1342308177&partnerID=8YFLogxK

U2 - 10.1016/S0140-6736(04)15597-9

DO - 10.1016/S0140-6736(04)15597-9

M3 - Article

VL - 363

SP - 631

EP - 639

JO - The Lancet

JF - The Lancet

SN - 0140-6736

IS - 9409

ER -