Wiedemann et al. demonstrate that Stat5a and Stat5b are induced by IL-12 and STAT4 signaling in NK cells following MCMV infection. They further provide evidence that the cytokines IL-2 and IL-15 upstream of STAT5 differentially promote the early and late stages of the adaptive NK cell response to MCMV infection.
- clonal expansion
- NK cell
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)