Disulfiram Hepatitis

Steven J. Morris; Robert Kanner; Robert O. Chiprut; Eugene R. Schiff

doi:10.1016/0016-5085(78)93772-1

Disulfiram Hepatitis

Steven J. Morris, Robert Kanner, Robert O. Chiprut, Eugene R. Schiff

Medicine

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

A case of an adult with disulfiram-induced hepatitis is presented. An etiological role for the drug was proved when the patient underwent a provocative challenge and developed evidence of hepatocellular damage, reversible on withdrawal of the drug. Disulfiram-induced liver injury is difficult to detect in a population with a high incidence of alcohol related hepatic disease. Liver chemistries should be screened before beginning disulfiram therapy and periodically during treatment.

Original language	English (US)
Pages (from-to)	100-102
Number of pages	3
Journal	Gastroenterology
Volume	75
Issue number	1
DOIs	https://doi.org/10.1016/0016-5085(78)93772-1
State	Published - 1978

ASJC Scopus subject areas

Hepatology
Gastroenterology

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title = "Disulfiram Hepatitis",

abstract = "A case of an adult with disulfiram-induced hepatitis is presented. An etiological role for the drug was proved when the patient underwent a provocative challenge and developed evidence of hepatocellular damage, reversible on withdrawal of the drug. Disulfiram-induced liver injury is difficult to detect in a population with a high incidence of alcohol related hepatic disease. Liver chemistries should be screened before beginning disulfiram therapy and periodically during treatment.",

author = "Morris, {Steven J.} and Robert Kanner and Chiprut, {Robert O.} and Schiff, {Eugene R.}",

year = "1978",

doi = "10.1016/0016-5085(78)93772-1",

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pages = "100--102",

journal = "Gastroenterology",

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TY - JOUR

T1 - Disulfiram Hepatitis

AU - Morris, Steven J.

AU - Kanner, Robert

AU - Chiprut, Robert O.

AU - Schiff, Eugene R.

PY - 1978

Y1 - 1978

N2 - A case of an adult with disulfiram-induced hepatitis is presented. An etiological role for the drug was proved when the patient underwent a provocative challenge and developed evidence of hepatocellular damage, reversible on withdrawal of the drug. Disulfiram-induced liver injury is difficult to detect in a population with a high incidence of alcohol related hepatic disease. Liver chemistries should be screened before beginning disulfiram therapy and periodically during treatment.

AB - A case of an adult with disulfiram-induced hepatitis is presented. An etiological role for the drug was proved when the patient underwent a provocative challenge and developed evidence of hepatocellular damage, reversible on withdrawal of the drug. Disulfiram-induced liver injury is difficult to detect in a population with a high incidence of alcohol related hepatic disease. Liver chemistries should be screened before beginning disulfiram therapy and periodically during treatment.

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U2 - 10.1016/0016-5085(78)93772-1

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EP - 102

JO - Gastroenterology

JF - Gastroenterology

SN - 0016-5085

IS - 1

ER -

Disulfiram Hepatitis

Abstract

ASJC Scopus subject areas

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