The distribution of non covalently bound secretory component (SC) on the two subclasses, IgA f and IgA g of rabbit secretory IgA (sIgA) was determined; the two subclasses were separated from each other by the use of antibody immunosorbent columns and were subjected to SDS polyacrylamide gel electrophoresis. No SC appeared to be dissociated from the IgA f molecules from each of 11 different rabbits; the IgA g molecules, however, did have SC which was dissociated by SDS. Thus, all of the noncovalently bound SC on rabbit sIgA resides on the IgA g subclass molecules.
|Original language||English (US)|
|Number of pages||4|
|Journal||Journal of Immunology|
|State||Published - 1975|
ASJC Scopus subject areas
- Immunology and Allergy