Distortion-product otoacoustic emissions in nonacoustic tumors of the cerebellopontine angle

Steven Ross Mobley, Onur Odabasi, Syed Ahsan, Glen Martin, Bart Stagner, Fred F Telischi

Research output: Contribution to journalArticle

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Abstract

OBJECTIVES: The goal of the present study was to compare the frequencies of cochlear and noncochlear patterns of distortion-product otoacoustic emissions (DPOAEs) in patients with nonacoustic (non-AN) tumors of the cerebellopontine angle (CPA)/internal auditory canal with those in patients with acoustic neuroma (AN). STUDY DESIGN AND SETTING: We conducted a prospective study of patients with non-AN internal auditory canal/CPA tumors treated between 1992 and 1999 in a tertiary care setting. We collected data on behavioral pure tone average, speech discrimination score, acoustic immittance tests, DPOAEs, and tumor size. DPOAEs were divided into those with a cochlear or a noncochlear pattern. Comparisons were made with a control group of patients with AN of the CPA. RESULTS: Twenty-four patients were included in the study: 12 patients in the non-AN group and 12 patients in the AN group. In the non-AN group, 5 (42%) patients had a cochlear pattern and 7 (58%) had a noncochlear pattern. In the AN group, 7 (58%) patients had a cochlear pattern and 5 (42%) had a noncochlear pattern. The differences between the non-AN and AN groups were statistically significant. In the non-AN group, patients with a cochlear-pattern DPOAE had significantly smaller tumors (P = 0.03) and a trend (P = 0.07) toward higher speech discrimination score. Age and pure tone average were not significantly different in the non-AN tumor patients. In the AN group, none of the study parameters were significantly related to the pattern of DPOAE. CONCLUSIONS: ANs appear to differ from other tumors of the CPA in their propensity to cause sensory versus neural hearing loss. A larger series of patients would be useful to confirm these preliminary findings.

Original languageEnglish
Pages (from-to)115-120
Number of pages6
JournalOtolaryngology - Head and Neck Surgery
Volume126
Issue number2
DOIs
StatePublished - Feb 1 2002

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Acoustic Neuroma
Neuroma
Cochlea
Speech Perception
Neoplasms
Tertiary Healthcare
Hearing Loss
Acoustics
Prospective Studies

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Distortion-product otoacoustic emissions in nonacoustic tumors of the cerebellopontine angle. / Mobley, Steven Ross; Odabasi, Onur; Ahsan, Syed; Martin, Glen; Stagner, Bart; Telischi, Fred F.

In: Otolaryngology - Head and Neck Surgery, Vol. 126, No. 2, 01.02.2002, p. 115-120.

Research output: Contribution to journalArticle

Mobley, Steven Ross ; Odabasi, Onur ; Ahsan, Syed ; Martin, Glen ; Stagner, Bart ; Telischi, Fred F. / Distortion-product otoacoustic emissions in nonacoustic tumors of the cerebellopontine angle. In: Otolaryngology - Head and Neck Surgery. 2002 ; Vol. 126, No. 2. pp. 115-120.
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abstract = "OBJECTIVES: The goal of the present study was to compare the frequencies of cochlear and noncochlear patterns of distortion-product otoacoustic emissions (DPOAEs) in patients with nonacoustic (non-AN) tumors of the cerebellopontine angle (CPA)/internal auditory canal with those in patients with acoustic neuroma (AN). STUDY DESIGN AND SETTING: We conducted a prospective study of patients with non-AN internal auditory canal/CPA tumors treated between 1992 and 1999 in a tertiary care setting. We collected data on behavioral pure tone average, speech discrimination score, acoustic immittance tests, DPOAEs, and tumor size. DPOAEs were divided into those with a cochlear or a noncochlear pattern. Comparisons were made with a control group of patients with AN of the CPA. RESULTS: Twenty-four patients were included in the study: 12 patients in the non-AN group and 12 patients in the AN group. In the non-AN group, 5 (42{\%}) patients had a cochlear pattern and 7 (58{\%}) had a noncochlear pattern. In the AN group, 7 (58{\%}) patients had a cochlear pattern and 5 (42{\%}) had a noncochlear pattern. The differences between the non-AN and AN groups were statistically significant. In the non-AN group, patients with a cochlear-pattern DPOAE had significantly smaller tumors (P = 0.03) and a trend (P = 0.07) toward higher speech discrimination score. Age and pure tone average were not significantly different in the non-AN tumor patients. In the AN group, none of the study parameters were significantly related to the pattern of DPOAE. CONCLUSIONS: ANs appear to differ from other tumors of the CPA in their propensity to cause sensory versus neural hearing loss. A larger series of patients would be useful to confirm these preliminary findings.",
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AB - OBJECTIVES: The goal of the present study was to compare the frequencies of cochlear and noncochlear patterns of distortion-product otoacoustic emissions (DPOAEs) in patients with nonacoustic (non-AN) tumors of the cerebellopontine angle (CPA)/internal auditory canal with those in patients with acoustic neuroma (AN). STUDY DESIGN AND SETTING: We conducted a prospective study of patients with non-AN internal auditory canal/CPA tumors treated between 1992 and 1999 in a tertiary care setting. We collected data on behavioral pure tone average, speech discrimination score, acoustic immittance tests, DPOAEs, and tumor size. DPOAEs were divided into those with a cochlear or a noncochlear pattern. Comparisons were made with a control group of patients with AN of the CPA. RESULTS: Twenty-four patients were included in the study: 12 patients in the non-AN group and 12 patients in the AN group. In the non-AN group, 5 (42%) patients had a cochlear pattern and 7 (58%) had a noncochlear pattern. In the AN group, 7 (58%) patients had a cochlear pattern and 5 (42%) had a noncochlear pattern. The differences between the non-AN and AN groups were statistically significant. In the non-AN group, patients with a cochlear-pattern DPOAE had significantly smaller tumors (P = 0.03) and a trend (P = 0.07) toward higher speech discrimination score. Age and pure tone average were not significantly different in the non-AN tumor patients. In the AN group, none of the study parameters were significantly related to the pattern of DPOAE. CONCLUSIONS: ANs appear to differ from other tumors of the CPA in their propensity to cause sensory versus neural hearing loss. A larger series of patients would be useful to confirm these preliminary findings.

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