Dissociated vertical nystagmus and internuclear ophthalmoplegia from a midbrain infarction

Randolph S. Marshall, Ralph L. Sacco, J. P. Mohr, Ronald Kreuger, Jeffrey G. Odel

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

We describe a patient with a dissociated vertical nystagmus and an internuclear ophthalmoplegia. The vertical nystagmus consisted of a left downward nystagmus with a synchronous right intorting nystagmus when the patient looked down and to the left. This rare type of nystagmus has been described both in isolation and in association with an internuclear ophthalmoplegia. Previous authors postulated a lesion in the midbrain in the region of the medial longitudinal fasciculus. In our patient, a discrete midbrain infarction was demonstrated on magnetic resonance imaging in the hypothesized location, thus providing supportive anatomical evidence for a vertical gaze coordination pathway in the region of the medial longitudinal fasciculus.

Original languageEnglish (US)
Pages (from-to)1304-1305
Number of pages2
JournalArchives of neurology
Volume48
Issue number12
DOIs
StatePublished - Dec 1991
Externally publishedYes

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

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