Abstract
In patients with germinal aplasia or 'Sertoli cell only' syndrome (Del Castillo syndrome) basal FSH serum levels were higher in comparison with normal adult males; however, basal LH concentration was similar. Synthetic LRH administration elicited an augmented FSH response and normal LH response when compared to that observed in normal adult men. These data indicate that in cases of selective germinal aplasia in the presence of normal Sertoli and Leydig cells, the FSH secretory response to LRH is enhanced, which may reflect a separate gonadal feedback control for FSH and LH secretion.
| Original language | English |
|---|---|
| Pages (from-to) | 1125-1127 |
| Number of pages | 3 |
| Journal | Journal of Clinical Endocrinology and Metabolism |
| Volume | 38 |
| Issue number | 6 |
| State | Published - Dec 1 1974 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Biochemistry
- Endocrinology, Diabetes and Metabolism
Cite this
Disparity in the negative gonadal feedback control for LH and FSH secretion in cases of germinal aplasia or Sertoli cell only syndrome. / Zarate, A.; Garrido, J.; Canales, E. S.; Soria, J.; Schally, Andrew V.
In: Journal of Clinical Endocrinology and Metabolism, Vol. 38, No. 6, 01.12.1974, p. 1125-1127.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Disparity in the negative gonadal feedback control for LH and FSH secretion in cases of germinal aplasia or Sertoli cell only syndrome
AU - Zarate, A.
AU - Garrido, J.
AU - Canales, E. S.
AU - Soria, J.
AU - Schally, Andrew V
PY - 1974/12/1
Y1 - 1974/12/1
N2 - In patients with germinal aplasia or 'Sertoli cell only' syndrome (Del Castillo syndrome) basal FSH serum levels were higher in comparison with normal adult males; however, basal LH concentration was similar. Synthetic LRH administration elicited an augmented FSH response and normal LH response when compared to that observed in normal adult men. These data indicate that in cases of selective germinal aplasia in the presence of normal Sertoli and Leydig cells, the FSH secretory response to LRH is enhanced, which may reflect a separate gonadal feedback control for FSH and LH secretion.
AB - In patients with germinal aplasia or 'Sertoli cell only' syndrome (Del Castillo syndrome) basal FSH serum levels were higher in comparison with normal adult males; however, basal LH concentration was similar. Synthetic LRH administration elicited an augmented FSH response and normal LH response when compared to that observed in normal adult men. These data indicate that in cases of selective germinal aplasia in the presence of normal Sertoli and Leydig cells, the FSH secretory response to LRH is enhanced, which may reflect a separate gonadal feedback control for FSH and LH secretion.
UR - http://www.scopus.com/inward/record.url?scp=0016157605&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0016157605&partnerID=8YFLogxK
M3 - Article
C2 - 4831706
AN - SCOPUS:0016157605
VL - 38
SP - 1125
EP - 1127
JO - Journal of Clinical Endocrinology and Metabolism
JF - Journal of Clinical Endocrinology and Metabolism
SN - 0021-972X
IS - 6
ER -