Disparities in overall survival for male breast cancer patients in the state of Florida (1996-2007)

Bridget O'Brien, Tulay Sengul, Feng Miao, Constantine Saclarides, Stacey L. Tannenbaum, Hattan Alghamdi, David J Lee, Dido Franceschi, Margaret M Byrne, Eli Avisar

Research output: Contribution to journalArticle

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Abstract

Background Little is known regarding population-based disparities in male breast cancer (MBC). We analyzed this for Florida using data from 1996 to 2007. Materials and Methods Data from the Florida Cancer Data System, the Agency for Health Care Administration, and the US Census were linked for MBC patients (n = 1589). Survival time was our primary end point, with adjustments for sociodemographic status, neighborhood-based poverty measures, clinical and hospital characteristics, and comorbidity measures based on linkage with in- and outpatient treatment records. Survival time was modeled using univariate and multivariate Cox regression models. Results Five-year overall survival was 65.7%. Overall mean survival time in years was 7.7, but shorter in black (5.9) than white (7.8) individuals, in non-Hispanic (7.7) than Hispanic (8.5) individuals, and in the lowest socioeconomic status (SES) group (5.9) than in the highest (8.2) SES group. Patients with low SES also presented at a more advanced stage with only 75/175 [42.9%] of low SES patients who presented with localized disease compared with 311/621 [50.1%] for middle-high SES and 162/334 [48.5%] for the highest SES. Univariate hazard regressions found only the highest (hazard ratio [HR], 0.63; 95% confidence interval [CI], 0.46-0.85) and middle-high (HR, 0.71; 95% CI, 0.54-0.94) SES were at improved survival compared with lowest SES but this advantage did not remain significant in the fully adjusted model. Marital status, age, smoking status, stage, treatments, and comorbidities were also predictors of survival. Conclusion Survival disparities among SES groups were most apparent in our study. Improved access to screening and health care utilization might attenuate these differences. Understanding other survival disparities can aid in public health and clinical care choices.

Original languageEnglish (US)
Pages (from-to)e177-e187
JournalClinical Breast Cancer
Volume15
Issue number4
DOIs
StatePublished - 2015

Fingerprint

Male Breast Neoplasms
Social Class
Survival
Comorbidity
Patient Acceptance of Health Care
Confidence Intervals
Delivery of Health Care
Health Services Accessibility
Marital Status
Censuses
Poverty
Hispanic Americans
Proportional Hazards Models
Information Systems
Inpatients
Outpatients
Survival Rate
Public Health
Smoking

Keywords

  • Cancer disparity
  • Ethnic factor
  • Florida
  • Male breast cancer
  • Social factor

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Disparities in overall survival for male breast cancer patients in the state of Florida (1996-2007). / O'Brien, Bridget; Sengul, Tulay; Miao, Feng; Saclarides, Constantine; Tannenbaum, Stacey L.; Alghamdi, Hattan; Lee, David J; Franceschi, Dido; Byrne, Margaret M; Avisar, Eli.

In: Clinical Breast Cancer, Vol. 15, No. 4, 2015, p. e177-e187.

Research output: Contribution to journalArticle

O'Brien, Bridget ; Sengul, Tulay ; Miao, Feng ; Saclarides, Constantine ; Tannenbaum, Stacey L. ; Alghamdi, Hattan ; Lee, David J ; Franceschi, Dido ; Byrne, Margaret M ; Avisar, Eli. / Disparities in overall survival for male breast cancer patients in the state of Florida (1996-2007). In: Clinical Breast Cancer. 2015 ; Vol. 15, No. 4. pp. e177-e187.
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abstract = "Background Little is known regarding population-based disparities in male breast cancer (MBC). We analyzed this for Florida using data from 1996 to 2007. Materials and Methods Data from the Florida Cancer Data System, the Agency for Health Care Administration, and the US Census were linked for MBC patients (n = 1589). Survival time was our primary end point, with adjustments for sociodemographic status, neighborhood-based poverty measures, clinical and hospital characteristics, and comorbidity measures based on linkage with in- and outpatient treatment records. Survival time was modeled using univariate and multivariate Cox regression models. Results Five-year overall survival was 65.7{\%}. Overall mean survival time in years was 7.7, but shorter in black (5.9) than white (7.8) individuals, in non-Hispanic (7.7) than Hispanic (8.5) individuals, and in the lowest socioeconomic status (SES) group (5.9) than in the highest (8.2) SES group. Patients with low SES also presented at a more advanced stage with only 75/175 [42.9{\%}] of low SES patients who presented with localized disease compared with 311/621 [50.1{\%}] for middle-high SES and 162/334 [48.5{\%}] for the highest SES. Univariate hazard regressions found only the highest (hazard ratio [HR], 0.63; 95{\%} confidence interval [CI], 0.46-0.85) and middle-high (HR, 0.71; 95{\%} CI, 0.54-0.94) SES were at improved survival compared with lowest SES but this advantage did not remain significant in the fully adjusted model. Marital status, age, smoking status, stage, treatments, and comorbidities were also predictors of survival. Conclusion Survival disparities among SES groups were most apparent in our study. Improved access to screening and health care utilization might attenuate these differences. Understanding other survival disparities can aid in public health and clinical care choices.",
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T1 - Disparities in overall survival for male breast cancer patients in the state of Florida (1996-2007)

AU - O'Brien, Bridget

AU - Sengul, Tulay

AU - Miao, Feng

AU - Saclarides, Constantine

AU - Tannenbaum, Stacey L.

AU - Alghamdi, Hattan

AU - Lee, David J

AU - Franceschi, Dido

AU - Byrne, Margaret M

AU - Avisar, Eli

PY - 2015

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N2 - Background Little is known regarding population-based disparities in male breast cancer (MBC). We analyzed this for Florida using data from 1996 to 2007. Materials and Methods Data from the Florida Cancer Data System, the Agency for Health Care Administration, and the US Census were linked for MBC patients (n = 1589). Survival time was our primary end point, with adjustments for sociodemographic status, neighborhood-based poverty measures, clinical and hospital characteristics, and comorbidity measures based on linkage with in- and outpatient treatment records. Survival time was modeled using univariate and multivariate Cox regression models. Results Five-year overall survival was 65.7%. Overall mean survival time in years was 7.7, but shorter in black (5.9) than white (7.8) individuals, in non-Hispanic (7.7) than Hispanic (8.5) individuals, and in the lowest socioeconomic status (SES) group (5.9) than in the highest (8.2) SES group. Patients with low SES also presented at a more advanced stage with only 75/175 [42.9%] of low SES patients who presented with localized disease compared with 311/621 [50.1%] for middle-high SES and 162/334 [48.5%] for the highest SES. Univariate hazard regressions found only the highest (hazard ratio [HR], 0.63; 95% confidence interval [CI], 0.46-0.85) and middle-high (HR, 0.71; 95% CI, 0.54-0.94) SES were at improved survival compared with lowest SES but this advantage did not remain significant in the fully adjusted model. Marital status, age, smoking status, stage, treatments, and comorbidities were also predictors of survival. Conclusion Survival disparities among SES groups were most apparent in our study. Improved access to screening and health care utilization might attenuate these differences. Understanding other survival disparities can aid in public health and clinical care choices.

AB - Background Little is known regarding population-based disparities in male breast cancer (MBC). We analyzed this for Florida using data from 1996 to 2007. Materials and Methods Data from the Florida Cancer Data System, the Agency for Health Care Administration, and the US Census were linked for MBC patients (n = 1589). Survival time was our primary end point, with adjustments for sociodemographic status, neighborhood-based poverty measures, clinical and hospital characteristics, and comorbidity measures based on linkage with in- and outpatient treatment records. Survival time was modeled using univariate and multivariate Cox regression models. Results Five-year overall survival was 65.7%. Overall mean survival time in years was 7.7, but shorter in black (5.9) than white (7.8) individuals, in non-Hispanic (7.7) than Hispanic (8.5) individuals, and in the lowest socioeconomic status (SES) group (5.9) than in the highest (8.2) SES group. Patients with low SES also presented at a more advanced stage with only 75/175 [42.9%] of low SES patients who presented with localized disease compared with 311/621 [50.1%] for middle-high SES and 162/334 [48.5%] for the highest SES. Univariate hazard regressions found only the highest (hazard ratio [HR], 0.63; 95% confidence interval [CI], 0.46-0.85) and middle-high (HR, 0.71; 95% CI, 0.54-0.94) SES were at improved survival compared with lowest SES but this advantage did not remain significant in the fully adjusted model. Marital status, age, smoking status, stage, treatments, and comorbidities were also predictors of survival. Conclusion Survival disparities among SES groups were most apparent in our study. Improved access to screening and health care utilization might attenuate these differences. Understanding other survival disparities can aid in public health and clinical care choices.

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KW - Ethnic factor

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KW - Male breast cancer

KW - Social factor

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