The establishment of chromosomal sex (46, XY or 46, XX) is considered the first step in normal sexual differentiation. However, the first sexual structures that form may be considered as either primordial or neutral. The term sex determination refers to the process in which the primordial gonad is committed to development as testis or ovary. Sex differentiation refers to the development of the internal accessory duct structures and external genitalia (1-5).
|Original language||English (US)|
|Title of host publication||Pediatric Endocrinology, Fifth Edition|
|Subtitle of host publication||Volume 2 Growth, Adrenal, Sexual, Thyroid, Calcium, and Fluid Balance Disorders|
|Number of pages||26|
|State||Published - Jan 1 2006|
ASJC Scopus subject areas