Disorders of sexual differentiation

Adriana A. Carrillo, Middey Damian, Gary Berkovitz

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations


The establishment of chromosomal sex (46, XY or 46, XX) is considered the first step in normal sexual differentiation. However, the first sexual structures that form may be considered as either primordial or neutral. The term sex determination refers to the process in which the primordial gonad is committed to development as testis or ovary. Sex differentiation refers to the development of the internal accessory duct structures and external genitalia (1-5).

Original languageEnglish (US)
Title of host publicationPediatric Endocrinology, Fifth Edition
Subtitle of host publicationVolume 2 Growth, Adrenal, Sexual, Thyroid, Calcium, and Fluid Balance Disorders
PublisherCRC Press
Number of pages26
ISBN (Electronic)9781420042726
ISBN (Print)9781420042702
StatePublished - Jan 1 2006

ASJC Scopus subject areas

  • Medicine(all)


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