Direct holmium laser-assisted balloon angioplasty in acute myocardial infarction

Eduardo de Marchena, Stephen Mallon, Juan D. Posada, Katherine Garvey-Patsias, Bipin Joshi, Louis Correa, Rafael F. Sequeira, Douglas Murphy-Chutorian, Robert J. Myerburg

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


The holmium laser (Thulium-Holmium-Chromium: yttrium-aluminum garnet [YAG]laser) system was recently introduced for the treatment of atherosclerotic peripheral arterial and coronary artery lesions.1-6 This pulsed mid-infrared laser (2.1 μm) ablates atherosclerotic tissue without significant thermal damage to adjacent tissue.2,3,6,7 This study was designed to test the hypothesis that delivery characteristics of and tissue sensitivities to holmium laser energy make it a feasible treatment option in patients with acute myocardial infarction, with thrombosis and atherosclerotic plaque. In this report, we provide data on the first 3 cases of direct laserassisted balloon angioplasty during an acute myocardial infarction.

Original languageEnglish (US)
Pages (from-to)1223-1225
Number of pages3
JournalThe American Journal of Cardiology
Issue number13
StatePublished - May 15 1993

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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