Digital processing with a three-state molecular switch

Francisco Raymo, Silvia Giordani, Andrew J P White, David J. Williams

Research output: Contribution to journalArticle

157 Citations (Scopus)

Abstract

Certain molecular switches respond to input stimulations producing detectable outputs. The interplay of these signals can be exploited to reproduce basic logic operations at the molecular level. The transition from simple logic gates to complex digital circuits requires the design of chemical systems able to process multiple inputs and outputs. We have identified a three-state molecular switch that responds to one chemical and two optical inputs producing two optical outputs. We have encoded binary digits in its inputs and outputs applying positive logic conventions and demonstrated that this chemical system converts three-digit input strings into two-digit output strings. The logic function executed by the three-state molecular switch is equivalent to that of a combinational logic circuit integrating two AND, two NOT, and one OR gate. The three states of the molecular switch are a colorless spiropyran, a purple trans-merocyanine, and its yellow-green protonated form. We have elucidated their structures by X-ray crystallography, 1H NMR spectroscopy, COSY and NOE experiments, as well as density functional calculations. The three input stimulations controlling the interconversion of the three states of the molecular switch are ultraviolet light, visible light, and H+. The two outputs are the absorption bands in the visible region of the two colored states of the molecular switch. We have monitored the switching processes and quantified the associated thermodynamic and kinetic parameters with the aid of 1H NMR and visible absorption spectroscopies.

Original languageEnglish
Pages (from-to)4158-4169
Number of pages12
JournalJournal of Organic Chemistry
Volume68
Issue number11
DOIs
StatePublished - May 30 2003

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Digital signal processing
Switches
Combinatorial circuits
Logic gates
X ray crystallography
Logic circuits
Digital circuits
Absorption spectroscopy
Kinetic parameters
Nuclear magnetic resonance spectroscopy
Density functional theory
Absorption spectra
Nuclear magnetic resonance
Thermodynamics
Experiments

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Digital processing with a three-state molecular switch. / Raymo, Francisco; Giordani, Silvia; White, Andrew J P; Williams, David J.

In: Journal of Organic Chemistry, Vol. 68, No. 11, 30.05.2003, p. 4158-4169.

Research output: Contribution to journalArticle

Raymo, F, Giordani, S, White, AJP & Williams, DJ 2003, 'Digital processing with a three-state molecular switch', Journal of Organic Chemistry, vol. 68, no. 11, pp. 4158-4169. https://doi.org/10.1021/jo0340455
Raymo, Francisco ; Giordani, Silvia ; White, Andrew J P ; Williams, David J. / Digital processing with a three-state molecular switch. In: Journal of Organic Chemistry. 2003 ; Vol. 68, No. 11. pp. 4158-4169.
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