Diffuse optical imaging of brain activation to joint attention experience

Banghe Zhu, Nitin Yadav, Gustavo Rey, Anuradha Godavarty

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

In the early development of social cognition and language, infants tend to participate in face-to-face interactions engaging in joint attention exchanges. Joint attention is vital to social competence at all ages, lacking which is a primary feature to distinguish autistic from non-autistic population. In this study, diffuse optical imaging is used for the first time to investigate the joint attention experience in normal adults. Imaging studies were performed in the frontal regions of the brain (BA9 and BA10) in order to study the differences in the brain activation in response to video clips corresponding to joint attention based skills. The frontal regions of the brain were non-invasively imaged using a novel optical cap coupled to a frequency-domain optical imaging system. The statistical analysis from 11 normal adult subjects, with three repetitions from each subject, indicated that the averaged changes in the cerebral blood oxygenation levels were different under the joint and non-joint attention based stimulus. The preliminary studies demonstrate the feasibility of implementing diffuse optical imaging towards autism-related research to study the brain activation in response to socio-communication skills.

Original languageEnglish (US)
Pages (from-to)32-39
Number of pages8
JournalBehavioural Brain Research
Volume202
Issue number1
DOIs
StatePublished - Aug 24 2009

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Optical Imaging
Brain
Optical Devices
Feasibility Studies
Autistic Disorder
Surgical Instruments
Cognition
Language
Joints
Communication
Research
Population

Keywords

  • Brain activation
  • Diffuse optical imaging
  • Hemodynamic response
  • Joint attention
  • Near-infrared spectroscopy

ASJC Scopus subject areas

  • Behavioral Neuroscience

Cite this

Diffuse optical imaging of brain activation to joint attention experience. / Zhu, Banghe; Yadav, Nitin; Rey, Gustavo; Godavarty, Anuradha.

In: Behavioural Brain Research, Vol. 202, No. 1, 24.08.2009, p. 32-39.

Research output: Contribution to journalArticle

Zhu, Banghe ; Yadav, Nitin ; Rey, Gustavo ; Godavarty, Anuradha. / Diffuse optical imaging of brain activation to joint attention experience. In: Behavioural Brain Research. 2009 ; Vol. 202, No. 1. pp. 32-39.
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