Diffuse large B-cell lymphoma: Insights gained from gene expression profiling

Izidore S. Lossos, Ronald Levy

Research output: Contribution to journalReview article

13 Scopus citations

Abstract

Analysis of global gene expression with DNA microarrays has great potential to improve the understanding of tumorigenesis, advance tumor diagnosis and classification, and affect cancer treatment. Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's lymphoma. However, we now realize that the disease is extremely heterogeneous. This review summarizes the progress in understanding DLBCL that has been made as a result of the application of gene expression profiling.

Original languageEnglish (US)
Pages (from-to)321-329
Number of pages9
JournalInternational journal of hematology
Volume77
Issue number4
DOIs
StatePublished - May 2003

Keywords

  • Diffuse large B-cell lymphoma
  • Gene expression profiling
  • HGAL

ASJC Scopus subject areas

  • Hematology

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