Differential penetration of ototopicals and water through tympanostomy tubes

Lee P. Smith, Jennifer L. Smullen, Ramzi T Younis

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Objective: To evaluate the penetration of ototopicals and water through tympanostomy tubes (TT) using a physical model. Study Design: An in vitro model was created to measure the ability of various solutions to penetrate a variety of TT. Methods: A TT was placed through a perforation (myringotomy) in a silastic sheet (tympanic membrane) fixed between the ends of two 1 mL syringes. Measurements were obtained of the maximum height various liquids (tap water, 2% soapy water, ocean water, ofloxacin otic, corticosporin otic, and ciprofloxacin/dexamethasone otic) achieved before penetrating different TTs (1.0 mm or 1.27 mm Paparella silicone, 1.14 mm or 1.27 mm Reuter Bobbin titanium, 1.27 mm Collar Button fluoroplastic or 1.14 mm T-type silicone). Results: Two percent soapy water was significantly more permeable than water and ocean water in all tubes studied. Ciprofloxacin/dexamethasone otic was significantly more permeable than tap water, ocean water, and ofloxacin otic in only the Collar Button fluoroplastic TT. Our results suggest that titanium TTs are more permeable than other TT. Otherwise, ototopicals, tap water, and ocean water behaved similarly across all TT studied. Conclusions: Our results demonstrate that ototopicals, tap water, and ocean water behave similarly with regard to TT penetration. Ciprofloxacin/dexamethasone otic may have better penetration than other ototopicals. Titanium TT may be easier to penetrate than other TT.

Original languageEnglish
Pages (from-to)1367-1370
Number of pages4
JournalLaryngoscope
Volume115
Issue number8
DOIs
StatePublished - Aug 1 2005

Fingerprint

Middle Ear Ventilation
Water
Ear
Oceans and Seas
Ciprofloxacin
Titanium
Dexamethasone
Ofloxacin
Silicones
Tympanic Membrane
Syringes

Keywords

  • Differential penetration
  • Otorrhea
  • Ototopicals
  • Tympanostomy tubes
  • Water precautions

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Differential penetration of ototopicals and water through tympanostomy tubes. / Smith, Lee P.; Smullen, Jennifer L.; Younis, Ramzi T.

In: Laryngoscope, Vol. 115, No. 8, 01.08.2005, p. 1367-1370.

Research output: Contribution to journalArticle

Smith, Lee P. ; Smullen, Jennifer L. ; Younis, Ramzi T. / Differential penetration of ototopicals and water through tympanostomy tubes. In: Laryngoscope. 2005 ; Vol. 115, No. 8. pp. 1367-1370.
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