Differential fatigue of paralyzed thenar muscles by stimuli of different intensities

Sharlene Godfrey, Jane E. Butler, Lisa Griffin, Christine K Thomas

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Muscles paralyzed by injury or disease fatigue excessively when stimulated. This study examined whether the first few paralyzed thenar motor units recruited by electrical stimulation of the median nerve were more fatigue resistant than the total thenar motor unit population. The paralyzed thenar muscles of four subjects with chronic cervical spinal cord injury were fatigued by a 2-min intermittent 40-Hz protocol on 2 days. One experiment involved submaximal stimulation, the other supramaximal stimulation. These stimuli resulted in activation of part and all of the thenar muscles, respectively. Relative force loss, force-time integral decline, and slowing of half-relaxation time were always significantly less when only part rather than all of the muscles was fatigued. The part of the paralyzed muscles that was activated was also relatively fatigue resistant compared with control single thenar motor units. Thus, a reversal of recruitment order from fatigable to fatigue-resistant units cannot explain the extreme fatigability of paralyzed muscles. Use of submaximal stimulation during functional electrical stimulation may therefore help to reduce muscle fatigue because it recruits the more fatigue-resistant units.

Original languageEnglish
Pages (from-to)122-131
Number of pages10
JournalMuscle and Nerve
Volume26
Issue number1
DOIs
StatePublished - Jul 17 2002

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Fatigue
Muscles
Electric Stimulation
Muscle Fatigue
Median Nerve
Spinal Cord Injuries
Wounds and Injuries
Population

Keywords

  • Human
  • Median nerve stimulation
  • Motor unit recruitment
  • Spinal cord injury
  • Submaximal nerve stimulation

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Differential fatigue of paralyzed thenar muscles by stimuli of different intensities. / Godfrey, Sharlene; Butler, Jane E.; Griffin, Lisa; Thomas, Christine K.

In: Muscle and Nerve, Vol. 26, No. 1, 17.07.2002, p. 122-131.

Research output: Contribution to journalArticle

Godfrey, S, Butler, JE, Griffin, L & Thomas, CK 2002, 'Differential fatigue of paralyzed thenar muscles by stimuli of different intensities', Muscle and Nerve, vol. 26, no. 1, pp. 122-131. https://doi.org/10.1002/mus.10173
Godfrey, Sharlene ; Butler, Jane E. ; Griffin, Lisa ; Thomas, Christine K. / Differential fatigue of paralyzed thenar muscles by stimuli of different intensities. In: Muscle and Nerve. 2002 ; Vol. 26, No. 1. pp. 122-131.
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