Differences in the frequency of resistance to antiretroviral drug classes among human immunodeficiency virus type 1 clinical isolates

Rafael E. Campo, Paola N. Lichtenberger, Isabella Rosa, German Suarez, Fernando A. Rivera, Allan E. Rodriguez, Dushyantha T. Jayaweera, Natalie A. Wahlay, Michael A. Kolber

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4 Scopus citations

Abstract

Genotypic resistance to all antiretroviral classes was widespread among human immunodeficiency virus type 1 isolates failing therapy. Resistance to nonnucleoside reverse transcriptase inhibitors was found most frequently and resistance to protease inhibitors was found least frequently, most likely due to differences in the number of enzymatic amino acid substitutions leading to resistance to each particular drug class.

Original languageEnglish (US)
Pages (from-to)3376-3378
Number of pages3
JournalJournal of Clinical Microbiology
Volume41
Issue number7
DOIs
StatePublished - Jul 1 2003

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ASJC Scopus subject areas

  • Microbiology (medical)

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