Differences between cytoplasmic glucocorticoid binding proteins shown by heterogeneity of nuclear acceptor sites

Marc E Lippman, E. B. Thompson

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

In this report, evidence is presented that at least some degree of specificity of response may be mediated by subtle differences in the cytoplasmic corticosteroid binding proteins between tissues with differing kinds of responses to glucocorticoids. The data further suggest that there are intranuclear binding sites for cytoplasmic glucocorticoid receptors which are of high affinity and saturability and which can distinguish between glucocorticoid receptors of differing origin.

Original languageEnglish
Pages (from-to)352-355
Number of pages4
JournalNature
Volume246
Issue number5432
StatePublished - Dec 1 1973
Externally publishedYes

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Glucocorticoid Receptors
Glucocorticoids
Carrier Proteins
Cytoplasmic and Nuclear Receptors
Adrenal Cortex Hormones
Binding Sites

ASJC Scopus subject areas

  • General

Cite this

Differences between cytoplasmic glucocorticoid binding proteins shown by heterogeneity of nuclear acceptor sites. / Lippman, Marc E; Thompson, E. B.

In: Nature, Vol. 246, No. 5432, 01.12.1973, p. 352-355.

Research output: Contribution to journalArticle

Lippman, Marc E ; Thompson, E. B. / Differences between cytoplasmic glucocorticoid binding proteins shown by heterogeneity of nuclear acceptor sites. In: Nature. 1973 ; Vol. 246, No. 5432. pp. 352-355.
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