Abstract
Childhood cancer survivors are at increased risk of cardiovascular disease, in part because of adiposity. Whether survivors have healthy diets and whether dietary quality is associated with adiposity among survivors are not known. Survivors and siblings from the Cardiac Risk Factors in Childhood Cancer Survivors Study completed 3-day food records that were used to estimate daily caloric intake relative to recommended and dietary quality using the Healthy Eating Index-2005 (HEI). Medical records were reviewed for cancer therapies. Body composition was measured by dual-energy x-ray absorptiometry. Of 91 childhood cancer survivors and 30 sibling controls, there were no marked differences in mean daily caloric intakes (98% vs. 100% of recommended) or HEI total scores (55.5 vs. 53.3), respectively, with both groups scoring worst for the consumption of dark green vegetables and whole grains. Survivors exposed to cranial irradiation had lower total HEI scores (-6.4, P = 0.01). Among survivors, better dietary quality, as reflected by the total HEI score, was associated with decreasing percent body fat (β = -0.19, P = 0.04). Survivors consume diets similar to their siblings although these diets are only moderately adherent to current guidelines. Decreased dietary quality is associated with higher body fat and receipt of cranial irradiation in survivors.
| Original language | English |
|---|---|
| Pages (from-to) | 547-555 |
| Number of pages | 9 |
| Journal | Nutrition and Cancer |
| Volume | 65 |
| Issue number | 4 |
| DOIs | |
| State | Published - May 1 2013 |
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ASJC Scopus subject areas
- Medicine (miscellaneous)
- Nutrition and Dietetics
- Oncology
- Cancer Research
Cite this
Dietary quality, caloric intake, and adiposity of childhood cancer survivors and their siblings : An analysis from the cardiac risk factors in childhood cancer survivors study. / Landy, David C.; Lipsitz, Stuart R.; Kurtz, Joy M.; Hinkle, Andrea S.; Constine, Louis S.; Adams, M. Jacob; Lipshultz, Steven E; Miller, Tracie L.
In: Nutrition and Cancer, Vol. 65, No. 4, 01.05.2013, p. 547-555.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Dietary quality, caloric intake, and adiposity of childhood cancer survivors and their siblings
T2 - An analysis from the cardiac risk factors in childhood cancer survivors study
AU - Landy, David C.
AU - Lipsitz, Stuart R.
AU - Kurtz, Joy M.
AU - Hinkle, Andrea S.
AU - Constine, Louis S.
AU - Adams, M. Jacob
AU - Lipshultz, Steven E
AU - Miller, Tracie L
PY - 2013/5/1
Y1 - 2013/5/1
N2 - Childhood cancer survivors are at increased risk of cardiovascular disease, in part because of adiposity. Whether survivors have healthy diets and whether dietary quality is associated with adiposity among survivors are not known. Survivors and siblings from the Cardiac Risk Factors in Childhood Cancer Survivors Study completed 3-day food records that were used to estimate daily caloric intake relative to recommended and dietary quality using the Healthy Eating Index-2005 (HEI). Medical records were reviewed for cancer therapies. Body composition was measured by dual-energy x-ray absorptiometry. Of 91 childhood cancer survivors and 30 sibling controls, there were no marked differences in mean daily caloric intakes (98% vs. 100% of recommended) or HEI total scores (55.5 vs. 53.3), respectively, with both groups scoring worst for the consumption of dark green vegetables and whole grains. Survivors exposed to cranial irradiation had lower total HEI scores (-6.4, P = 0.01). Among survivors, better dietary quality, as reflected by the total HEI score, was associated with decreasing percent body fat (β = -0.19, P = 0.04). Survivors consume diets similar to their siblings although these diets are only moderately adherent to current guidelines. Decreased dietary quality is associated with higher body fat and receipt of cranial irradiation in survivors.
AB - Childhood cancer survivors are at increased risk of cardiovascular disease, in part because of adiposity. Whether survivors have healthy diets and whether dietary quality is associated with adiposity among survivors are not known. Survivors and siblings from the Cardiac Risk Factors in Childhood Cancer Survivors Study completed 3-day food records that were used to estimate daily caloric intake relative to recommended and dietary quality using the Healthy Eating Index-2005 (HEI). Medical records were reviewed for cancer therapies. Body composition was measured by dual-energy x-ray absorptiometry. Of 91 childhood cancer survivors and 30 sibling controls, there were no marked differences in mean daily caloric intakes (98% vs. 100% of recommended) or HEI total scores (55.5 vs. 53.3), respectively, with both groups scoring worst for the consumption of dark green vegetables and whole grains. Survivors exposed to cranial irradiation had lower total HEI scores (-6.4, P = 0.01). Among survivors, better dietary quality, as reflected by the total HEI score, was associated with decreasing percent body fat (β = -0.19, P = 0.04). Survivors consume diets similar to their siblings although these diets are only moderately adherent to current guidelines. Decreased dietary quality is associated with higher body fat and receipt of cranial irradiation in survivors.
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UR - http://www.scopus.com/inward/citedby.url?scp=84877979941&partnerID=8YFLogxK
U2 - 10.1080/01635581.2013.770042
DO - 10.1080/01635581.2013.770042
M3 - Article
C2 - 23659446
AN - SCOPUS:84877979941
VL - 65
SP - 547
EP - 555
JO - Nutrition and Cancer
JF - Nutrition and Cancer
SN - 0163-5581
IS - 4
ER -