Diagnostic uses of nuclear medicine in AIDS.

W. J. Vanarthos, W. I. Ganz, J. C. Vanarthos, Aldo N Serafini, J. Tehranzadeh

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Radionuclide imaging, if applied with an organ system approach, is useful in the diagnosis of the AIDS (acquired immunodeficiency syndrome)-related complex. Specific pathologic processes can be suspected on the basis of uptake patterns. The intensity and pattern of pulmonary uptake and concomitant nonpulmonary uptake of gallium provide guidelines for distinguishing among various opportunistic pulmonary pathogens. Gastrointestinal and extra-gastrointestinal tract uptake of gallium aids distinction among fungal, mycobacterial, and viral infections and neoplasms. Patterns of spleen uptake of technetium-99m sulfur colloid and gallium allow differentiation between neoplasm (Kaposi sarcoma) and infection (with mycobacteria). Skeletal and soft-tissue abnormalities can be characterized and differentiated on the basis of bone scan and other radionuclide scan findings. Thallium uptake in brain tumors (and not in areas of infection) allows brain lesion discrimination. In the proper clinical setting, AIDS nephropathy has a characteristic gallium uptake pattern. Cardiac abnormalities (including functional) can also be assessed with scintigraphy. With knowledge of these organ-specific patterns and with correlative imaging studies, the manifestations of AIDS can be differentiated and appropriate treatment instituted.

Original languageEnglish
Pages (from-to)731-749; discussion 749
JournalRadiographics : a review publication of the Radiological Society of North America, Inc
Volume12
Issue number4
StatePublished - Jul 1 1992

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Gallium
Nuclear Medicine
Acquired Immunodeficiency Syndrome
Radionuclide Imaging
Technetium Tc 99m Sulfur Colloid
Lung
Mycobacterium Infections
Mycoses
Thallium
Kaposi's Sarcoma
Technetium
Virus Diseases
Pathologic Processes
Brain Neoplasms
Radioisotopes
Gastrointestinal Tract
Neoplasms
Spleen
Guidelines
Bone and Bones

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Vanarthos, W. J., Ganz, W. I., Vanarthos, J. C., Serafini, A. N., & Tehranzadeh, J. (1992). Diagnostic uses of nuclear medicine in AIDS. Radiographics : a review publication of the Radiological Society of North America, Inc, 12(4), 731-749; discussion 749.

Diagnostic uses of nuclear medicine in AIDS. / Vanarthos, W. J.; Ganz, W. I.; Vanarthos, J. C.; Serafini, Aldo N; Tehranzadeh, J.

In: Radiographics : a review publication of the Radiological Society of North America, Inc, Vol. 12, No. 4, 01.07.1992, p. 731-749; discussion 749.

Research output: Contribution to journalArticle

Vanarthos, WJ, Ganz, WI, Vanarthos, JC, Serafini, AN & Tehranzadeh, J 1992, 'Diagnostic uses of nuclear medicine in AIDS.', Radiographics : a review publication of the Radiological Society of North America, Inc, vol. 12, no. 4, pp. 731-749; discussion 749.
Vanarthos WJ, Ganz WI, Vanarthos JC, Serafini AN, Tehranzadeh J. Diagnostic uses of nuclear medicine in AIDS. Radiographics : a review publication of the Radiological Society of North America, Inc. 1992 Jul 1;12(4):731-749; discussion 749.
Vanarthos, W. J. ; Ganz, W. I. ; Vanarthos, J. C. ; Serafini, Aldo N ; Tehranzadeh, J. / Diagnostic uses of nuclear medicine in AIDS. In: Radiographics : a review publication of the Radiological Society of North America, Inc. 1992 ; Vol. 12, No. 4. pp. 731-749; discussion 749.
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