Diagnostic studies in patients with sickle cell anemia and acute abdominal pain

Aldo N Serafini, G. Spoliansky, George N Sfakianakis, B. Montalvo, W. N. Jensen

Research output: Contribution to journalArticle

Abstract

Twenty-eight patients with sickle cell disease who presented with acute abdominal pain were evaluated with clinical laboratory, ultrasound, and biliary scintigraphic studies to determine their predictive capabilities for differentiating venoocclusive disease (sickle cell crisis) from acute biliary disease. Eleven patients were treated surgically and 17 medically. Gallstones were demonstrated in 25 (90%) of the patients studied by ultrasound, and biliary scans were abnormal in nine patients (32%). Abnormal laboratory and radiological studies (ultrasound, biliary scintigraphy) were not significantly different in the two groups and had a low positive predictive value for detection of acute biliary disease. Nevertheless, normal biliary scintigraphy had high negative predictive value in that, if normal, it gave assurance that the cystic duct was patent and unnecessary surgery could be obviated in this high-risk category of patients.

Original languageEnglish
Pages (from-to)1061-1062
Number of pages2
JournalArchives of Internal Medicine
Volume147
Issue number6
DOIs
StatePublished - Sep 25 1987

Fingerprint

Acute Pain
Sickle Cell Anemia
Abdominal Pain
Acute Disease
Radionuclide Imaging
Unnecessary Procedures
Cystic Duct
Gallstones
Reference Values

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Diagnostic studies in patients with sickle cell anemia and acute abdominal pain. / Serafini, Aldo N; Spoliansky, G.; Sfakianakis, George N; Montalvo, B.; Jensen, W. N.

In: Archives of Internal Medicine, Vol. 147, No. 6, 25.09.1987, p. 1061-1062.

Research output: Contribution to journalArticle

Serafini, Aldo N ; Spoliansky, G. ; Sfakianakis, George N ; Montalvo, B. ; Jensen, W. N. / Diagnostic studies in patients with sickle cell anemia and acute abdominal pain. In: Archives of Internal Medicine. 1987 ; Vol. 147, No. 6. pp. 1061-1062.
@article{14e80c8e81bf407b8742a142e62dc376,
title = "Diagnostic studies in patients with sickle cell anemia and acute abdominal pain",
abstract = "Twenty-eight patients with sickle cell disease who presented with acute abdominal pain were evaluated with clinical laboratory, ultrasound, and biliary scintigraphic studies to determine their predictive capabilities for differentiating venoocclusive disease (sickle cell crisis) from acute biliary disease. Eleven patients were treated surgically and 17 medically. Gallstones were demonstrated in 25 (90{\%}) of the patients studied by ultrasound, and biliary scans were abnormal in nine patients (32{\%}). Abnormal laboratory and radiological studies (ultrasound, biliary scintigraphy) were not significantly different in the two groups and had a low positive predictive value for detection of acute biliary disease. Nevertheless, normal biliary scintigraphy had high negative predictive value in that, if normal, it gave assurance that the cystic duct was patent and unnecessary surgery could be obviated in this high-risk category of patients.",
author = "Serafini, {Aldo N} and G. Spoliansky and Sfakianakis, {George N} and B. Montalvo and Jensen, {W. N.}",
year = "1987",
month = "9",
day = "25",
doi = "10.1001/archinte.147.6.1061",
language = "English",
volume = "147",
pages = "1061--1062",
journal = "JAMA Internal Medicine",
issn = "2168-6106",
publisher = "American Medical Association",
number = "6",

}

TY - JOUR

T1 - Diagnostic studies in patients with sickle cell anemia and acute abdominal pain

AU - Serafini, Aldo N

AU - Spoliansky, G.

AU - Sfakianakis, George N

AU - Montalvo, B.

AU - Jensen, W. N.

PY - 1987/9/25

Y1 - 1987/9/25

N2 - Twenty-eight patients with sickle cell disease who presented with acute abdominal pain were evaluated with clinical laboratory, ultrasound, and biliary scintigraphic studies to determine their predictive capabilities for differentiating venoocclusive disease (sickle cell crisis) from acute biliary disease. Eleven patients were treated surgically and 17 medically. Gallstones were demonstrated in 25 (90%) of the patients studied by ultrasound, and biliary scans were abnormal in nine patients (32%). Abnormal laboratory and radiological studies (ultrasound, biliary scintigraphy) were not significantly different in the two groups and had a low positive predictive value for detection of acute biliary disease. Nevertheless, normal biliary scintigraphy had high negative predictive value in that, if normal, it gave assurance that the cystic duct was patent and unnecessary surgery could be obviated in this high-risk category of patients.

AB - Twenty-eight patients with sickle cell disease who presented with acute abdominal pain were evaluated with clinical laboratory, ultrasound, and biliary scintigraphic studies to determine their predictive capabilities for differentiating venoocclusive disease (sickle cell crisis) from acute biliary disease. Eleven patients were treated surgically and 17 medically. Gallstones were demonstrated in 25 (90%) of the patients studied by ultrasound, and biliary scans were abnormal in nine patients (32%). Abnormal laboratory and radiological studies (ultrasound, biliary scintigraphy) were not significantly different in the two groups and had a low positive predictive value for detection of acute biliary disease. Nevertheless, normal biliary scintigraphy had high negative predictive value in that, if normal, it gave assurance that the cystic duct was patent and unnecessary surgery could be obviated in this high-risk category of patients.

UR - http://www.scopus.com/inward/record.url?scp=0023260488&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023260488&partnerID=8YFLogxK

U2 - 10.1001/archinte.147.6.1061

DO - 10.1001/archinte.147.6.1061

M3 - Article

C2 - 3296981

VL - 147

SP - 1061

EP - 1062

JO - JAMA Internal Medicine

JF - JAMA Internal Medicine

SN - 2168-6106

IS - 6

ER -