Diagnostic and therapeutic approach to pancreatic cancer

J. S. Barkin, J. A. Goldstein

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

Adenocarcinoma of the pancreas ranks fourth as a cause of cancer death in adults in the United States and is the second most common cause of cancer deaths of all GI-related carcinomas. It usually presents late in its course. The clinical features are discussed, with emphasis on those that allow early detection of the disease, as well as a review of diagnostic methods and pre- and perioperative staging, which will allow the appropriate application of surgical and palliative therapeutic modalities. Despite the significant progress that has been made, further research studies are needed to advance our therapeutic approach to this aggressive cancer. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

Original languageEnglish (US)
Pages (from-to)400-409
Number of pages10
JournalBiomedicine and Pharmacotherapy
Volume54
Issue number7
DOIs
StatePublished - Jan 1 2000

Keywords

  • Adenocarcinoma
  • K-ras gene mutation
  • Pancreas
  • Pancreatitis
  • Unresectable and resectable

ASJC Scopus subject areas

  • Pharmacology

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