Diagnostic and management strategies in patients with persistent fetal vasculature: Current insights

Supalert Prakhunhungsit, Audina M. Berrocal

Research output: Contribution to journalReview articlepeer-review

Abstract

Persistent fetal vasculature (PFV), previously known as persistent hyperplastic primary vitreous, is a developmental malformation of the eyes that is caused by a failure of the hyaloid vasculature to regress in utero. PFV has been reported for decades; however, our understanding of the pathophysiology/pathogenesis of PFV, and the diagnostic and treatment modalities for PFV have evolved over time, and these advancements have improved diag-nosis, treatment, and outcomes. However and in spite of these advancements, the heterogeneity of this disease continues to make PFV a diagnostic challenge. Here, we review what is currently known about various important aspects of PFV to update and enhance the knowledge of ophthalmologists who encounter and manage PFV in clinical practice.

Original languageEnglish (US)
Pages (from-to)4325-4335
Number of pages11
JournalClinical Ophthalmology
Volume14
DOIs
StatePublished - 2020

Keywords

  • Current insights
  • Diagnostic and management strategies
  • PFV
  • Persistent fetal vasculature

ASJC Scopus subject areas

  • Ophthalmology

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