TY - JOUR
T1 - Diagnostic and management strategies in patients with persistent fetal vasculature
T2 - Current insights
AU - Prakhunhungsit, Supalert
AU - Berrocal, Audina M.
N1 - Publisher Copyright:
© 2020 Prakhunhungsit and Berrocal.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020
Y1 - 2020
N2 - Persistent fetal vasculature (PFV), previously known as persistent hyperplastic primary vitreous, is a developmental malformation of the eyes that is caused by a failure of the hyaloid vasculature to regress in utero. PFV has been reported for decades; however, our understanding of the pathophysiology/pathogenesis of PFV, and the diagnostic and treatment modalities for PFV have evolved over time, and these advancements have improved diag-nosis, treatment, and outcomes. However and in spite of these advancements, the heterogeneity of this disease continues to make PFV a diagnostic challenge. Here, we review what is currently known about various important aspects of PFV to update and enhance the knowledge of ophthalmologists who encounter and manage PFV in clinical practice.
AB - Persistent fetal vasculature (PFV), previously known as persistent hyperplastic primary vitreous, is a developmental malformation of the eyes that is caused by a failure of the hyaloid vasculature to regress in utero. PFV has been reported for decades; however, our understanding of the pathophysiology/pathogenesis of PFV, and the diagnostic and treatment modalities for PFV have evolved over time, and these advancements have improved diag-nosis, treatment, and outcomes. However and in spite of these advancements, the heterogeneity of this disease continues to make PFV a diagnostic challenge. Here, we review what is currently known about various important aspects of PFV to update and enhance the knowledge of ophthalmologists who encounter and manage PFV in clinical practice.
KW - Current insights
KW - Diagnostic and management strategies
KW - PFV
KW - Persistent fetal vasculature
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U2 - 10.2147/OPTH.S236117
DO - 10.2147/OPTH.S236117
M3 - Review article
AN - SCOPUS:85097669766
VL - 14
SP - 4325
EP - 4335
JO - Clinical Ophthalmology
JF - Clinical Ophthalmology
SN - 1177-5467
ER -