Diagnosis and Management of Barrett-Related Neoplasia in the Modern Era

Lysandra Voltaggio, Elizabeth A. Montgomery

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations

Abstract

Whereas in the past, pathologists were hesitant to diagnose high-grade dysplasia in patients with Barrett esophagus, because this diagnosis prompted esophagectomy, current international consensus is that endoscopic treatment is the management for high-grade dysplasia and intramucosal carcinoma. Furthermore, many centers advocate endoscopic ablation for low-grade dysplasia. As such, establishing a diagnosis of dysplasia has become the key step; separation between the grades of dysplasia is less critical. This article offers some criteria for separating dysplasia from reactive changes, discusses pitfalls in interpreting endoscopic mucosal resection specimens, and outlines management strategies.

Original languageEnglish (US)
Pages (from-to)781-800
Number of pages20
JournalSurgical Pathology Clinics
Volume10
Issue number4
DOIs
StatePublished - Dec 2017
Externally publishedYes

Keywords

  • Barrett dysplasia
  • Barrett neoplasia
  • Endoscopic mucosal resection
  • Endoscopic submucosal dissection
  • Radiofrequency ablation

ASJC Scopus subject areas

  • Surgery
  • Pathology and Forensic Medicine

Fingerprint

Dive into the research topics of 'Diagnosis and Management of Barrett-Related Neoplasia in the Modern Era'. Together they form a unique fingerprint.

Cite this