Diabetic peripheral neuropathic pain: Clinical and quality-of-life issues

Charles E. Argoff, B. Eliot Cole, David A Fishbain, Gordon A. Irving

Research output: Contribution to journalArticle

160 Citations (Scopus)

Abstract

Diabetic peripheral neuropathy (DPN) is estimated to be present In 50% of people living with diabetes mellitus (DM). Comorbidities of DM, such as macrovascular and microvascular changes, also Interact with DPN and affect Its course. In patients with DM, DPN is the leading causa of foot ulcers, which In turn are a major cause of amputation In the United States. Although most patients with DPN do not have pain, approximately 11.% of patients with DPN have chronic, painful symptoms that diminish quality of life, disrupt sleep, and can lead to depression. Despite the number of patients affected by DPN pain, little consensus exists about the pathophysiology, best diagnostic tools, and primary treatment choices. This article reviews the current knowledge about and presents recommendations for diagnostic assessment of DPN pain based on a review of the literature.

Original languageEnglish
JournalMayo Clinic Proceedings
Volume81
Issue number4 SUPPL.
StatePublished - Jan 1 2006

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Diabetic Neuropathies
Neuralgia
Peripheral Nervous System Diseases
Quality of Life
Diabetes Mellitus
Pain
Foot Ulcer
Amputation
Comorbidity
Consensus
Sleep
Depression

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Argoff, C. E., Cole, B. E., Fishbain, D. A., & Irving, G. A. (2006). Diabetic peripheral neuropathic pain: Clinical and quality-of-life issues. Mayo Clinic Proceedings, 81(4 SUPPL.).

Diabetic peripheral neuropathic pain : Clinical and quality-of-life issues. / Argoff, Charles E.; Cole, B. Eliot; Fishbain, David A; Irving, Gordon A.

In: Mayo Clinic Proceedings, Vol. 81, No. 4 SUPPL., 01.01.2006.

Research output: Contribution to journalArticle

Argoff, CE, Cole, BE, Fishbain, DA & Irving, GA 2006, 'Diabetic peripheral neuropathic pain: Clinical and quality-of-life issues', Mayo Clinic Proceedings, vol. 81, no. 4 SUPPL..
Argoff CE, Cole BE, Fishbain DA, Irving GA. Diabetic peripheral neuropathic pain: Clinical and quality-of-life issues. Mayo Clinic Proceedings. 2006 Jan 1;81(4 SUPPL.).
Argoff, Charles E. ; Cole, B. Eliot ; Fishbain, David A ; Irving, Gordon A. / Diabetic peripheral neuropathic pain : Clinical and quality-of-life issues. In: Mayo Clinic Proceedings. 2006 ; Vol. 81, No. 4 SUPPL.
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