Abstract
Diabetic peripheral neuropathy (DPN) is estimated to be present In 50% of people living with diabetes mellitus (DM). Comorbidities of DM, such as macrovascular and microvascular changes, also Interact with DPN and affect Its course. In patients with DM, DPN is the leading causa of foot ulcers, which In turn are a major cause of amputation In the United States. Although most patients with DPN do not have pain, approximately 11.% of patients with DPN have chronic, painful symptoms that diminish quality of life, disrupt sleep, and can lead to depression. Despite the number of patients affected by DPN pain, little consensus exists about the pathophysiology, best diagnostic tools, and primary treatment choices. This article reviews the current knowledge about and presents recommendations for diagnostic assessment of DPN pain based on a review of the literature.
| Original language | English |
|---|---|
| Journal | Mayo Clinic Proceedings |
| Volume | 81 |
| Issue number | 4 SUPPL. |
| State | Published - Jan 1 2006 |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Diabetic peripheral neuropathic pain : Clinical and quality-of-life issues. / Argoff, Charles E.; Cole, B. Eliot; Fishbain, David A; Irving, Gordon A.
In: Mayo Clinic Proceedings, Vol. 81, No. 4 SUPPL., 01.01.2006.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Diabetic peripheral neuropathic pain
T2 - Clinical and quality-of-life issues
AU - Argoff, Charles E.
AU - Cole, B. Eliot
AU - Fishbain, David A
AU - Irving, Gordon A.
PY - 2006/1/1
Y1 - 2006/1/1
N2 - Diabetic peripheral neuropathy (DPN) is estimated to be present In 50% of people living with diabetes mellitus (DM). Comorbidities of DM, such as macrovascular and microvascular changes, also Interact with DPN and affect Its course. In patients with DM, DPN is the leading causa of foot ulcers, which In turn are a major cause of amputation In the United States. Although most patients with DPN do not have pain, approximately 11.% of patients with DPN have chronic, painful symptoms that diminish quality of life, disrupt sleep, and can lead to depression. Despite the number of patients affected by DPN pain, little consensus exists about the pathophysiology, best diagnostic tools, and primary treatment choices. This article reviews the current knowledge about and presents recommendations for diagnostic assessment of DPN pain based on a review of the literature.
AB - Diabetic peripheral neuropathy (DPN) is estimated to be present In 50% of people living with diabetes mellitus (DM). Comorbidities of DM, such as macrovascular and microvascular changes, also Interact with DPN and affect Its course. In patients with DM, DPN is the leading causa of foot ulcers, which In turn are a major cause of amputation In the United States. Although most patients with DPN do not have pain, approximately 11.% of patients with DPN have chronic, painful symptoms that diminish quality of life, disrupt sleep, and can lead to depression. Despite the number of patients affected by DPN pain, little consensus exists about the pathophysiology, best diagnostic tools, and primary treatment choices. This article reviews the current knowledge about and presents recommendations for diagnostic assessment of DPN pain based on a review of the literature.
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UR - http://www.scopus.com/inward/citedby.url?scp=33645657561&partnerID=8YFLogxK
M3 - Article
C2 - 16608048
AN - SCOPUS:33645657561
VL - 81
JO - Mayo Clinic Proceedings
JF - Mayo Clinic Proceedings
SN - 0025-6196
IS - 4 SUPPL.
ER -