Development of difference between red and white muscles in sensitivity to Ca2+ in the rabbit from embryo to adult

W. Glenn Kerrick, D. Secrist, R. Coby, S. Lucas

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Ca2+ binding to troponin in red and white muscles does not entirely determine the sensitivity of these muscles to Ca2+, in spite of indications by previous biochemical experiments; that differences either in the troponin molecule or in light chains of myosin, or other unknown factors are responsible for the difference in sensitivity of calcium between the two types of muscles; and that molecular changes from embryo to adult change the Ca2+ sensitivity in red muscle. These data show the importance of using muscles of one type in experiments designed to show the exact molecular mechanism for activation of a contraction by Ca2+.

Original languageEnglish
Pages (from-to)440-441
Number of pages2
JournalNature
Volume260
Issue number5550
StatePublished - Dec 1 1976
Externally publishedYes

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Embryonic Structures
Rabbits
Muscles
Troponin
Myosin Light Chains
Calcium

ASJC Scopus subject areas

  • General

Cite this

Development of difference between red and white muscles in sensitivity to Ca2+ in the rabbit from embryo to adult. / Kerrick, W. Glenn; Secrist, D.; Coby, R.; Lucas, S.

In: Nature, Vol. 260, No. 5550, 01.12.1976, p. 440-441.

Research output: Contribution to journalArticle

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