Abstract
Objective: To report a case of diabetic ketoacidosis induced by megestrol acetate in a patient with AIDS. Case Summary: A 46-year-old Haitian man arrived at our tuberculosis clinic with a 1-week history of difficulty walking, confusion, nuchal rigidity, and incontinence. On admission to the hospital, diabetic ketoacidosis was diagnosed, and appropriate treatment was started. The patient did not have a history of hyperglycemia, diabetes, or antiretroviral therapy that may have predisposed him to glucose intolerance. However, 6 weeks before admission, he was prescribed megestrol acetate suspension for anorexia. Discussion: Several cases of hyperglycemia induced by megestrol acetate in AIDS patients have been reported. However, to our knowledge, this is the first report of a patient presenting with diabetic ketoacidosis secondary to megestrol acetate therapy. Conclusions: In AIDS patients with cachexia who exhibit signs and symptoms of hyperglycemia without an obvious cause, megestrol acetate therapy may need to be discontinued.
| Original language | English |
|---|---|
| Pages (from-to) | 106-109 |
| Number of pages | 4 |
| Journal | Journal of Pharmacy Technology |
| Volume | 14 |
| Issue number | 3 |
| State | Published - May 1 1998 |
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ASJC Scopus subject areas
- Pharmaceutical Science
Cite this
Development of diabetic ketoacidosis in an AIDS patient being treated with megestrol acetate for cachexia. / White, Gina E.; Rodriguez, Allan E; Butt, Malmood Almed; Lijfrock, Virgil R.
In: Journal of Pharmacy Technology, Vol. 14, No. 3, 01.05.1998, p. 106-109.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Development of diabetic ketoacidosis in an AIDS patient being treated with megestrol acetate for cachexia
AU - White, Gina E.
AU - Rodriguez, Allan E
AU - Butt, Malmood Almed
AU - Lijfrock, Virgil R.
PY - 1998/5/1
Y1 - 1998/5/1
N2 - Objective: To report a case of diabetic ketoacidosis induced by megestrol acetate in a patient with AIDS. Case Summary: A 46-year-old Haitian man arrived at our tuberculosis clinic with a 1-week history of difficulty walking, confusion, nuchal rigidity, and incontinence. On admission to the hospital, diabetic ketoacidosis was diagnosed, and appropriate treatment was started. The patient did not have a history of hyperglycemia, diabetes, or antiretroviral therapy that may have predisposed him to glucose intolerance. However, 6 weeks before admission, he was prescribed megestrol acetate suspension for anorexia. Discussion: Several cases of hyperglycemia induced by megestrol acetate in AIDS patients have been reported. However, to our knowledge, this is the first report of a patient presenting with diabetic ketoacidosis secondary to megestrol acetate therapy. Conclusions: In AIDS patients with cachexia who exhibit signs and symptoms of hyperglycemia without an obvious cause, megestrol acetate therapy may need to be discontinued.
AB - Objective: To report a case of diabetic ketoacidosis induced by megestrol acetate in a patient with AIDS. Case Summary: A 46-year-old Haitian man arrived at our tuberculosis clinic with a 1-week history of difficulty walking, confusion, nuchal rigidity, and incontinence. On admission to the hospital, diabetic ketoacidosis was diagnosed, and appropriate treatment was started. The patient did not have a history of hyperglycemia, diabetes, or antiretroviral therapy that may have predisposed him to glucose intolerance. However, 6 weeks before admission, he was prescribed megestrol acetate suspension for anorexia. Discussion: Several cases of hyperglycemia induced by megestrol acetate in AIDS patients have been reported. However, to our knowledge, this is the first report of a patient presenting with diabetic ketoacidosis secondary to megestrol acetate therapy. Conclusions: In AIDS patients with cachexia who exhibit signs and symptoms of hyperglycemia without an obvious cause, megestrol acetate therapy may need to be discontinued.
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M3 - Article
VL - 14
SP - 106
EP - 109
JO - Journal of Pharmacy Technology
JF - Journal of Pharmacy Technology
SN - 8755-1225
IS - 3
ER -