Development of a total prosthetic urinary bladder

J. Kline, E. C. Eckstein, Norman L Block

Research output: Chapter in Book/Report/Conference proceedingChapter

11 Scopus citations


A total, implantable, prosthetic urinary bladder has been developed which empties without any external power. A prosthetic bladder would be of use in the estimated 40,000 cases of bladder cancer that will be diagnosed this year. Approximately one-fourth of these cases will eventually require removal and replacement of the bladder. Surgical treatment of advanced genital cancer, especially cervical cancer, also often requires removal and replacement of the urinary bladder. At the present time when the biologic bladder is removed, a substitute is constructed from a section of the intestinal tract. Construction of the substitute requires a significant portion of operating time (3 hrs). Additionally, a number of complications ensue from the use of intestine as a material source. An 'off the shelf' prosthetic bladder would greatly shorten the surgical treatment and eliminate the complications caused by use of intestinal material. In addition, a class of patients who would not survive the current surgical procedure would become eligible for surgical therapy.

Original languageEnglish
Title of host publicationTransactions of the American Society for Artificial Organs
Number of pages3
StatePublished - Dec 1 1978

ASJC Scopus subject areas

  • Medicine(all)


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