TY - JOUR
T1 - Devastating intracardiac and aortic thrombosis
T2 - A case report of apparent catastrophic antiphospholipid syndrome during liver transplantation
AU - Gologorsky, Edward
AU - Andrews, David M.
AU - Gologorsky, Angela
AU - Sampathi, Venkata
AU - Sundararaman, Lalitha
AU - Govindaswamy, Radhika
AU - Raveh, Yehuda
AU - Tzakis, Andreas G.
AU - Pretto, Ernesto A.
N1 - Copyright:
Copyright 2012 Elsevier B.V., All rights reserved.
PY - 2011/8
Y1 - 2011/8
N2 - Fewer than 80 cases of intracardiac thrombosis and intraoperative pulmonary thromboembolism during liver transplantation have been described. We present a patient who suffered an intraoperative fulminant intracardiac and aortic thrombosis and posthumously was found to have had high anticardiolipin immunoglobulin M concentration and markers of hyperfibrinolysis in preoperatively collected plasma. Hemostatic therapy in the presence of circulating antiphospholipid antibodies and the pathogenesis of a catastrophic antiphospholipid syndrome are discussed.
AB - Fewer than 80 cases of intracardiac thrombosis and intraoperative pulmonary thromboembolism during liver transplantation have been described. We present a patient who suffered an intraoperative fulminant intracardiac and aortic thrombosis and posthumously was found to have had high anticardiolipin immunoglobulin M concentration and markers of hyperfibrinolysis in preoperatively collected plasma. Hemostatic therapy in the presence of circulating antiphospholipid antibodies and the pathogenesis of a catastrophic antiphospholipid syndrome are discussed.
KW - Antiphospholipid syndrome
KW - Aortic thrombosis
KW - Hemostatic therapy
KW - Intracardiac thrombosis
KW - Intraoperative pulmonary thromboembolism
KW - Liver transplantation
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U2 - 10.1016/j.jclinane.2010.07.007
DO - 10.1016/j.jclinane.2010.07.007
M3 - Article
C2 - 21741809
AN - SCOPUS:79960943441
VL - 23
SP - 398
EP - 402
JO - Journal of Clinical Anesthesia
JF - Journal of Clinical Anesthesia
SN - 0952-8180
IS - 5
ER -