Determination of the number-average molecular weight of polysaccharides by end-group reduction with borohydride-t

G. N. Richards, W. J. Whelan

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

The reduction with sodium borohydride-t of a series of maltose oligosaccharides yields products whose residual radioactivity (after deduction of a blank) has a linear dependence on degree of polymerisation. The procedure has been extended to measure the average degree of polymerisation (or alternatively Mn) of hydrolysed amyloses. For this purpose, it is necessary to use a washing procedure to remove a radioactive impurity in the sodium borohydride. The method should be applicable to measurement of number-average molecular weights of any polysaccharide which has a reducing end-group.

Original languageEnglish (US)
Pages (from-to)185-191
Number of pages7
JournalCarbohydrate Research
Volume27
Issue number1
DOIs
StatePublished - Mar 1973

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

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