Determination of the minimum alveolar concentration (MAC) of halothane in the white New Zealand rabbit

N. L. Davis; R. L. Nunnally; T. I. Malinin

doi:10.1093/bja/47.3.341

Determination of the minimum alveolar concentration (MAC) of halothane in the white New Zealand rabbit

N. L. Davis, R. L. Nunnally, T. I. Malinin

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14 Scopus citations

Abstract

The minimum alveolar concentration (MAC) was determined in rabbits as the mean of the lowest alveolar halothane concentration preventing and the highest permitting a response to stimulus. MAC for the rabbit was 0.8 ± 0.3%. The measurement of MAC in the rabbit appears to reflect the arterial and brain anesthetic concentrations.

Original language	English (US)
Pages (from-to)	341-345
Number of pages	5
Journal	British Journal of Anaesthesia
Volume	47
Issue number	3
DOIs	https://doi.org/10.1093/bja/47.3.341
State	Published - Mar 1975
Externally published	Yes

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

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title = "Determination of the minimum alveolar concentration (MAC) of halothane in the white New Zealand rabbit",

abstract = "The minimum alveolar concentration (MAC) was determined in rabbits as the mean of the lowest alveolar halothane concentration preventing and the highest permitting a response to stimulus. MAC for the rabbit was 0.8 ± 0.3%. The measurement of MAC in the rabbit appears to reflect the arterial and brain anesthetic concentrations.",

author = "Davis, {N. L.} and Nunnally, {R. L.} and Malinin, {T. I.}",

year = "1975",

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N2 - The minimum alveolar concentration (MAC) was determined in rabbits as the mean of the lowest alveolar halothane concentration preventing and the highest permitting a response to stimulus. MAC for the rabbit was 0.8 ± 0.3%. The measurement of MAC in the rabbit appears to reflect the arterial and brain anesthetic concentrations.

AB - The minimum alveolar concentration (MAC) was determined in rabbits as the mean of the lowest alveolar halothane concentration preventing and the highest permitting a response to stimulus. MAC for the rabbit was 0.8 ± 0.3%. The measurement of MAC in the rabbit appears to reflect the arterial and brain anesthetic concentrations.

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Determination of the minimum alveolar concentration (MAC) of halothane in the white New Zealand rabbit

Abstract

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