Detection of low avidity anti‐dna antibodies in systemic lupus erythematosus

Richard L. Riley; Hugh Mcgrath; Ronald P. Taylor

doi:10.1002/art.1780220303

Detection of low avidity anti‐dna antibodies in systemic lupus erythematosus

Richard L. Riley, Hugh Mcgrath, Ronald P. Taylor

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

The binding of sonicated, radiolabeled DNA by systemic lupus erythematosus (SLE) sera was measured by a high sensitivity polyethylene glycol (PEG) precipitation assay. This method is considerably more sensitive than currently used techniques. The results suggest that a significant concentration of low avidity antibodies is present in SLE sera; however, these antibodies are not detected by conventional techniques.

Original language	English (US)
Pages (from-to)	219-225
Number of pages	7
Journal	Arthritis & Rheumatism
Volume	22
Issue number	3
DOIs	https://doi.org/10.1002/art.1780220303
State	Published - Mar 1979
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Rheumatology
Immunology
Pharmacology (medical)

Access to Document

10.1002/art.1780220303

Cite this

@article{bf3ac4201c0b4fdc92eae6d1aa787f34,

title = "Detection of low avidity anti‐dna antibodies in systemic lupus erythematosus",

abstract = "The binding of sonicated, radiolabeled DNA by systemic lupus erythematosus (SLE) sera was measured by a high sensitivity polyethylene glycol (PEG) precipitation assay. This method is considerably more sensitive than currently used techniques. The results suggest that a significant concentration of low avidity antibodies is present in SLE sera; however, these antibodies are not detected by conventional techniques.",

author = "Riley, {Richard L.} and Hugh Mcgrath and Taylor, {Ronald P.}",

year = "1979",

month = mar,

doi = "10.1002/art.1780220303",

language = "English (US)",

volume = "22",

pages = "219--225",

journal = "Arthritis care and research : the official journal of the Arthritis Health Professions Association",

issn = "2326-5191",

publisher = "John Wiley and Sons Ltd",

number = "3",

}

TY - JOUR

T1 - Detection of low avidity anti‐dna antibodies in systemic lupus erythematosus

AU - Riley, Richard L.

AU - Mcgrath, Hugh

AU - Taylor, Ronald P.

PY - 1979/3

Y1 - 1979/3

N2 - The binding of sonicated, radiolabeled DNA by systemic lupus erythematosus (SLE) sera was measured by a high sensitivity polyethylene glycol (PEG) precipitation assay. This method is considerably more sensitive than currently used techniques. The results suggest that a significant concentration of low avidity antibodies is present in SLE sera; however, these antibodies are not detected by conventional techniques.

AB - The binding of sonicated, radiolabeled DNA by systemic lupus erythematosus (SLE) sera was measured by a high sensitivity polyethylene glycol (PEG) precipitation assay. This method is considerably more sensitive than currently used techniques. The results suggest that a significant concentration of low avidity antibodies is present in SLE sera; however, these antibodies are not detected by conventional techniques.

UR - http://www.scopus.com/inward/record.url?scp=0018374277&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018374277&partnerID=8YFLogxK

U2 - 10.1002/art.1780220303

DO - 10.1002/art.1780220303

M3 - Article

C2 - 311203

AN - SCOPUS:0018374277

VL - 22

SP - 219

EP - 225

JO - Arthritis care and research : the official journal of the Arthritis Health Professions Association

JF - Arthritis care and research : the official journal of the Arthritis Health Professions Association

SN - 2326-5191

IS - 3

ER -

Detection of low avidity anti‐dna antibodies in systemic lupus erythematosus

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this