Detection and correction of frequency instabilities for volumetric 1H echo-planar spectroscopic imaging

Andreas Ebel, Andrew A. Maudsley

Research output: Contribution to journalArticlepeer-review

54 Scopus citations


Spectral quality in 1H magnetic resonance spectroscopic imaging (MRSI) critically depends on the stability of the main magnetic field. For echo-planar MRSI implemented at 3 T, temperature variation in the passive steel shims of the magnet system can lead to a significant drift in the resonance frequency. A method is presented that incorporates interleaved measurement of the instantaneous resonance frequency of a reference water signal into a volumetric MRSI sequence and allows correction for the drift during postprocessing. Results from normal human brain at 3 T indicate that the correction largely removes lineshape distortions, recovers metabolite signal loss, and improves spectral quality by reducing the width of spectral lines; however, particularly in inferior regions, other sources of distortion may be present that cause broadening of spectral lines.

Original languageEnglish (US)
Pages (from-to)465-469
Number of pages5
JournalMagnetic Resonance in Medicine
Issue number2
StatePublished - Feb 2005


  • Brain
  • EPSI
  • Frequency drift
  • In vivo MR spectroscopic imaging
  • Instrumental instabilities

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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