Desmoplastic small round cell tumor with primary ovarian involvement: Case report and review

Brian M. Slomovitz, Monica Girotra, Alexander Aledo, Anjali Saqi, Robert A. Soslow, Nitsana A. Spigland, Thomas A. Caputo

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

Background. Desmoplastic small round cell tumor (DSRCT) is a rare, aggressive, malignant neoplasm that has recently been characterized. It has not been associated with a primary visceral organ. In women, cases are even more rare and often have some ovarian involvement. Case. An 11-year-old girl presented with abdominal pain, nausea, and vomiting. A CT scan revealed a large heterogeneous pelvic mass with cystic components and an 8-cm midabdominal mass. During exploratory laparotomy, the patient was found to have a pelvic mass measuring 12.9 cm replacing normal ovarian tissue. The midabdominal mass was also removed. Pathology, cytology, and immunohistochemistry confirmed a desmoplastic small round cell tumor. Even with aggressive surgical and medical intervention, the patient died 11 months after initial diagnosis. Conclusion. We present a rare small cell tumor that is associated with ovarian involvement. The prognosis in these patients is extremely poor and very few survivals have been reported. (C) 2000 Academic Press.

Original languageEnglish (US)
Pages (from-to)124-128
Number of pages5
JournalGynecologic oncology
Volume79
Issue number1
DOIs
StatePublished - Jan 1 2000
Externally publishedYes

Keywords

  • Desmoplastic small round cell tumor
  • Immunohistochemistry
  • Ovarian neoplasm
  • Small cell carcinoma

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology

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  • Cite this

    Slomovitz, B. M., Girotra, M., Aledo, A., Saqi, A., Soslow, R. A., Spigland, N. A., & Caputo, T. A. (2000). Desmoplastic small round cell tumor with primary ovarian involvement: Case report and review. Gynecologic oncology, 79(1), 124-128. https://doi.org/10.1006/gyno.2000.5829