Design improvement in keratoprosthesis

Franck Villain, Emmanuel Lacombe, Jean Marc Legeais, Gilles Bos, Pascal Rol, Jean Marie Parel

Research output: Contribution to journalConference articlepeer-review

1 Scopus citations


One of the major problems of keratoprosthesis (KPro) is postoperative expulsion resulting from inadequate haptic fixation. To overcome this obstacle, a new design was conceived using a retrocorneal fixation. An earlier version of our KPro was made of 2 pieces: an optical element threaded in a surrounding haptic. Both pieces were made of medical grade PMMA. Although encouraging results were obtained, some anatomic failures occurred (20% at 5 years). To improve fixation and sealing, a biocolonizable skirt was recently added to the keratoprosthesis. This skirt should prevent migration of biocontaminants inside the eye. Made of porous PTFE, the skirt was ultrasonically held inside a one-piece PMMA keratoprosthesis by ultrasonic microwelding. Thus far, implantations carried out in 8 patients (5 month follow-up) show a good tolerance.

Original languageEnglish (US)
Pages (from-to)346-352
Number of pages7
JournalProceedings of SPIE - The International Society for Optical Engineering
StatePublished - Jun 23 1994
EventOphthalmic Technologies IV 1994 - Los Angeles, United States
Duration: Jan 23 1994Jan 29 1994

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


Dive into the research topics of 'Design improvement in keratoprosthesis'. Together they form a unique fingerprint.

Cite this