Design and conduct of clinical trials in osteoarthritis

R. D. Altman

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Clinical features of osteoarthritis (OA) require that general recommendations for the design and conduct of clinical trials be modified in order to apply these concepts to clinical trials in OA. A format has been devised for design of clinical trials in OA. In order to assess the applicability of this format, it has been compared to a published clinical trial: chondroprotec-tive agents versus standard treatment of OA of the knee. The published study appeared reliably designed and conducted in a manner that provided an answer to most of the questions posed. The study appears to form a sound basis for additional studies.

Original languageEnglish (US)
Pages (from-to)24-27
Number of pages4
JournalScandinavian Journal of Rheumatology
Issue numberS81
StatePublished - 1990
Externally publishedYes

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology


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