Dermatopathic lymphadenitis. The spectrum and significance of its morphologic features

E. Gould, R. Porto, J. Albores-Saavedra, M. J. Ibe

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

The lymph nodes from 50 axillary node dissections were evaluated by light microscopy and immunohistochemistry for the presence of dermatopathic lymphadenitis-like histologic features. On the basis of hematoxylin-eosin-stained sections alone, a histologic continuum was observed ranging from minimal paracortical changes to fully developed dermatopathic lymphadenitis. Twenty-three lymph node biopsies previously interpreted as diagnostic of dermatopathic lymphadenitis were reviewed. Only nine of these showed the fully developed dermatopathic lymphadenitis. Only one of these patients had a dermatitis. Our conclusions are that the presence of dermatopathic lymphadenitis does not mean that the patient has concomitant skin disease, and that axillary lymph nodes from patients without skin disease manifest a spectrum of dermatopathic lymphadenitis-like histologic features. Dermatopathic lymphadenitis may represent one end of a normally occurring histologic spectrum that may be found in the absence of a dermatitis.

Original languageEnglish (US)
Pages (from-to)1145-1150
Number of pages6
JournalArchives of Pathology and Laboratory Medicine
Volume112
Issue number11
StatePublished - Jan 1 1988

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

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    Gould, E., Porto, R., Albores-Saavedra, J., & Ibe, M. J. (1988). Dermatopathic lymphadenitis. The spectrum and significance of its morphologic features. Archives of Pathology and Laboratory Medicine, 112(11), 1145-1150.