Depressive disorders in epilepsy

Andres M Kanner, Juan Carlos Rivas Nieto

Research output: Contribution to journalArticle

138 Citations (Scopus)

Abstract

Depression is a common occurrence among epileptic patients and constitutes, along with anxiety disorders, the most frequent psychiatric condition in these patients. The relationship between depression and epilepsy is two-directional, because patients with major depression also have a higher frequency of epilepsy. In epileptic patients, depressive disorders can present as unipolar, bipolar, or dysthymic disorders. More characteristically, however, they present as an atypical depression, which can often go unrecognized for long periods of time. In the diagnostic evaluation of these patients, clinicians must rule out the possibility that the depressive disorder resulted from the administration of antiepileptic drugs (AEDs; e.g., barbiturates) or from the discontinuation of an AED with mood-stabilizing properties that were masking an underlying affective disorder. Although antidepressant drugs have been used in epileptic patients for a long time, to date there has only been one controlled study. The antidepressants of the family of selective serotonin reuptake inhibitors (SSRIs) should be considered as initial therapy for depressive disorders in these patients.

Original languageEnglish (US)
JournalNeurology
Volume53
Issue numberSUPPL. 2
StatePublished - Sep 22 1999
Externally publishedYes

Fingerprint

Depressive Disorder
Epilepsy
Depression
Antidepressive Agents
Dysthymic Disorder
Barbiturates
Serotonin Uptake Inhibitors
Anxiety Disorders
Mood Disorders
Bipolar Disorder
Anticonvulsants
Psychiatry

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Kanner, A. M., & Nieto, J. C. R. (1999). Depressive disorders in epilepsy. Neurology, 53(SUPPL. 2).

Depressive disorders in epilepsy. / Kanner, Andres M; Nieto, Juan Carlos Rivas.

In: Neurology, Vol. 53, No. SUPPL. 2, 22.09.1999.

Research output: Contribution to journalArticle

Kanner, AM & Nieto, JCR 1999, 'Depressive disorders in epilepsy', Neurology, vol. 53, no. SUPPL. 2.
Kanner AM, Nieto JCR. Depressive disorders in epilepsy. Neurology. 1999 Sep 22;53(SUPPL. 2).
Kanner, Andres M ; Nieto, Juan Carlos Rivas. / Depressive disorders in epilepsy. In: Neurology. 1999 ; Vol. 53, No. SUPPL. 2.
@article{2b8f55407feb499495e1f14459100812,
title = "Depressive disorders in epilepsy",
abstract = "Depression is a common occurrence among epileptic patients and constitutes, along with anxiety disorders, the most frequent psychiatric condition in these patients. The relationship between depression and epilepsy is two-directional, because patients with major depression also have a higher frequency of epilepsy. In epileptic patients, depressive disorders can present as unipolar, bipolar, or dysthymic disorders. More characteristically, however, they present as an atypical depression, which can often go unrecognized for long periods of time. In the diagnostic evaluation of these patients, clinicians must rule out the possibility that the depressive disorder resulted from the administration of antiepileptic drugs (AEDs; e.g., barbiturates) or from the discontinuation of an AED with mood-stabilizing properties that were masking an underlying affective disorder. Although antidepressant drugs have been used in epileptic patients for a long time, to date there has only been one controlled study. The antidepressants of the family of selective serotonin reuptake inhibitors (SSRIs) should be considered as initial therapy for depressive disorders in these patients.",
author = "Kanner, {Andres M} and Nieto, {Juan Carlos Rivas}",
year = "1999",
month = "9",
day = "22",
language = "English (US)",
volume = "53",
journal = "Neurology",
issn = "0028-3878",
publisher = "Lippincott Williams and Wilkins",
number = "SUPPL. 2",

}

TY - JOUR

T1 - Depressive disorders in epilepsy

AU - Kanner, Andres M

AU - Nieto, Juan Carlos Rivas

PY - 1999/9/22

Y1 - 1999/9/22

N2 - Depression is a common occurrence among epileptic patients and constitutes, along with anxiety disorders, the most frequent psychiatric condition in these patients. The relationship between depression and epilepsy is two-directional, because patients with major depression also have a higher frequency of epilepsy. In epileptic patients, depressive disorders can present as unipolar, bipolar, or dysthymic disorders. More characteristically, however, they present as an atypical depression, which can often go unrecognized for long periods of time. In the diagnostic evaluation of these patients, clinicians must rule out the possibility that the depressive disorder resulted from the administration of antiepileptic drugs (AEDs; e.g., barbiturates) or from the discontinuation of an AED with mood-stabilizing properties that were masking an underlying affective disorder. Although antidepressant drugs have been used in epileptic patients for a long time, to date there has only been one controlled study. The antidepressants of the family of selective serotonin reuptake inhibitors (SSRIs) should be considered as initial therapy for depressive disorders in these patients.

AB - Depression is a common occurrence among epileptic patients and constitutes, along with anxiety disorders, the most frequent psychiatric condition in these patients. The relationship between depression and epilepsy is two-directional, because patients with major depression also have a higher frequency of epilepsy. In epileptic patients, depressive disorders can present as unipolar, bipolar, or dysthymic disorders. More characteristically, however, they present as an atypical depression, which can often go unrecognized for long periods of time. In the diagnostic evaluation of these patients, clinicians must rule out the possibility that the depressive disorder resulted from the administration of antiepileptic drugs (AEDs; e.g., barbiturates) or from the discontinuation of an AED with mood-stabilizing properties that were masking an underlying affective disorder. Although antidepressant drugs have been used in epileptic patients for a long time, to date there has only been one controlled study. The antidepressants of the family of selective serotonin reuptake inhibitors (SSRIs) should be considered as initial therapy for depressive disorders in these patients.

UR - http://www.scopus.com/inward/record.url?scp=0033595436&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033595436&partnerID=8YFLogxK

M3 - Article

C2 - 10496231

AN - SCOPUS:0033595436

VL - 53

JO - Neurology

JF - Neurology

SN - 0028-3878

IS - SUPPL. 2

ER -