Depression in women treated for gynecological cancer: Clinical and neuroendocrine assessment

D. L. Evans, C. F. McCartney, C. B. Nemeroff, D. Raft, D. Quade, R. N. Golden, J. J. Haggerty, V. Holmes, J. S. Simon, M. Droba

Research output: Contribution to journalArticlepeer-review

87 Scopus citations


To determine the prevalence of major depression inn cancer patients and assess the usefulness of the dexamethasone suppression test (DST) and the thyrotropin-releasing hormone (TRH) stimulation test for diagnosing major depression in these patients, the authors studied 83 women hospitalized for gynecological cancer. Nineteen (23%) had major depression according to DSM-III criteria. The sensitivity and specificity of the DST were 40% and 88%, respectively. No relationship between DST and TRH test results was found. These findings indicate a high prevalence of depression in cancer patients, but further research on these tests in cancer patients is needed; their routine use with cancer patients is premature at this time.

Original languageEnglish (US)
Pages (from-to)447-452
Number of pages6
JournalAmerican Journal of Psychiatry
Issue number4
StatePublished - Jan 1 1986
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health


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