Depression in schizophrenia: Methodological artifact or distinct feature of the illness?

Eran Chemerinski, Christopher Bowie, Hannah Anderson, Philip D Harvey

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

In schizophrenia, there is a conceptual overlap between depressive and negative symptoms. This study examined the dimensional structure of depressive symptoms and their overlap with negative symptoms in a large sample of older medicated schizophrenia outpatients. Self-reported depression was obtained with the Beck Depression Inventory-II (BDI-II). Three components from this scale (i.e., dysphoria, psychosomatic and regret domains) showed excellent factorability and good consistency. However, adequate construct validity and correlates with outcomes were found for the dysphoria and regret domains, but not for the total score or the psychosomatic domain. Thus, the evaluation of domains within the BDI-II provides a more pure and clinically-relevant assessment of depressed mood in schizophrenia than the use of this scale as a whole.

Original languageEnglish
Pages (from-to)431-440
Number of pages10
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Volume20
Issue number4
StatePublished - Nov 1 2008
Externally publishedYes

Fingerprint

Artifacts
Schizophrenia
Depression
Emotions
Equipment and Supplies
Outpatients

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Neurology

Cite this

Depression in schizophrenia : Methodological artifact or distinct feature of the illness? / Chemerinski, Eran; Bowie, Christopher; Anderson, Hannah; Harvey, Philip D.

In: Journal of Neuropsychiatry and Clinical Neurosciences, Vol. 20, No. 4, 01.11.2008, p. 431-440.

Research output: Contribution to journalArticle

@article{cb953b0650ec4c61a8a049e760472aac,
title = "Depression in schizophrenia: Methodological artifact or distinct feature of the illness?",
abstract = "In schizophrenia, there is a conceptual overlap between depressive and negative symptoms. This study examined the dimensional structure of depressive symptoms and their overlap with negative symptoms in a large sample of older medicated schizophrenia outpatients. Self-reported depression was obtained with the Beck Depression Inventory-II (BDI-II). Three components from this scale (i.e., dysphoria, psychosomatic and regret domains) showed excellent factorability and good consistency. However, adequate construct validity and correlates with outcomes were found for the dysphoria and regret domains, but not for the total score or the psychosomatic domain. Thus, the evaluation of domains within the BDI-II provides a more pure and clinically-relevant assessment of depressed mood in schizophrenia than the use of this scale as a whole.",
author = "Eran Chemerinski and Christopher Bowie and Hannah Anderson and Harvey, {Philip D}",
year = "2008",
month = "11",
day = "1",
language = "English",
volume = "20",
pages = "431--440",
journal = "Journal of Neuropsychiatry and Clinical Neurosciences",
issn = "0895-0172",
publisher = "American Psychiatric Publishing Inc.",
number = "4",

}

TY - JOUR

T1 - Depression in schizophrenia

T2 - Methodological artifact or distinct feature of the illness?

AU - Chemerinski, Eran

AU - Bowie, Christopher

AU - Anderson, Hannah

AU - Harvey, Philip D

PY - 2008/11/1

Y1 - 2008/11/1

N2 - In schizophrenia, there is a conceptual overlap between depressive and negative symptoms. This study examined the dimensional structure of depressive symptoms and their overlap with negative symptoms in a large sample of older medicated schizophrenia outpatients. Self-reported depression was obtained with the Beck Depression Inventory-II (BDI-II). Three components from this scale (i.e., dysphoria, psychosomatic and regret domains) showed excellent factorability and good consistency. However, adequate construct validity and correlates with outcomes were found for the dysphoria and regret domains, but not for the total score or the psychosomatic domain. Thus, the evaluation of domains within the BDI-II provides a more pure and clinically-relevant assessment of depressed mood in schizophrenia than the use of this scale as a whole.

AB - In schizophrenia, there is a conceptual overlap between depressive and negative symptoms. This study examined the dimensional structure of depressive symptoms and their overlap with negative symptoms in a large sample of older medicated schizophrenia outpatients. Self-reported depression was obtained with the Beck Depression Inventory-II (BDI-II). Three components from this scale (i.e., dysphoria, psychosomatic and regret domains) showed excellent factorability and good consistency. However, adequate construct validity and correlates with outcomes were found for the dysphoria and regret domains, but not for the total score or the psychosomatic domain. Thus, the evaluation of domains within the BDI-II provides a more pure and clinically-relevant assessment of depressed mood in schizophrenia than the use of this scale as a whole.

UR - http://www.scopus.com/inward/record.url?scp=61849132273&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=61849132273&partnerID=8YFLogxK

M3 - Article

C2 - 19196927

AN - SCOPUS:61849132273

VL - 20

SP - 431

EP - 440

JO - Journal of Neuropsychiatry and Clinical Neurosciences

JF - Journal of Neuropsychiatry and Clinical Neurosciences

SN - 0895-0172

IS - 4

ER -