Depression and pegylated interferon-based hepatitis C treatment

Haris Papafragkakis, Murali S. Rao, Martin Moehlen, Sonu Dhillon, Paul Martin

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Interferon remains an essential component of treatment regimens for chronic hepatitis C infection. Mood disturbances, including depression, are relatively common in the hepatitis C virus-infected population and may worsen during hepatitis C treatment. Screening for depression prior to commencement of therapy is crucial and may improve treatment outcomes. Whether prophylactic antidepressant therapy should be initiated prior to therapy of hepatitis C virus infection with an interferon-based regimen remains unclear. We review the epidemiology, diagnosis, and management of depression before and during treatment of hepatitis C virus infection with interferon.

Original languageEnglish
Pages (from-to)25-35
Number of pages11
JournalInternational Journal of Interferon, Cytokine and Mediator Research
Volume4
Issue number1
StatePublished - Mar 27 2012

Fingerprint

Hepatitis C
Hepacivirus
Interferons
Virus Diseases
Depression
Chronic Hepatitis C
Antidepressive Agents
Epidemiology
Therapeutics
Infection
Population

Keywords

  • Cytokines
  • Depression
  • Hepatitis C
  • Pegylated interferon
  • Suicide risk

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

Cite this

Depression and pegylated interferon-based hepatitis C treatment. / Papafragkakis, Haris; Rao, Murali S.; Moehlen, Martin; Dhillon, Sonu; Martin, Paul.

In: International Journal of Interferon, Cytokine and Mediator Research, Vol. 4, No. 1, 27.03.2012, p. 25-35.

Research output: Contribution to journalArticle

Papafragkakis, Haris ; Rao, Murali S. ; Moehlen, Martin ; Dhillon, Sonu ; Martin, Paul. / Depression and pegylated interferon-based hepatitis C treatment. In: International Journal of Interferon, Cytokine and Mediator Research. 2012 ; Vol. 4, No. 1. pp. 25-35.
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