Abstract
Background: Cystic fibrosis (CF) is a chronic disease with an impact on the quality of life. Self-reported symptoms of depression and anxiety were assessed in the Spanish cohort of the International Epidemiological Study on Depression and Anxiety in patients with CF (International Depression-Anxiety Epidemiological Study) and their relationship with health status and health-related quality of life (HRQoL) was evaluated. Methods: This cross-sectional study recruited adult patients with CF at 10 Spanish centers. Patients completed the Hospital Anxiety and Depression Scale (HADS) and the Revised Cystic Fibrosis Questionnaire. Demographic and health data were recorded from medical charts. Logistic regression was used to determine the predictors of elevated symptoms of depression and anxiety (HADS. ≥. 8). Results: Of the 336 participants recruited (mean age, 28.1. years; 48.2% women), 41 (12.2%) had elevated depression-related scores, and 100 (29.7%) had elevated anxiety-related scores (HADS. ≥. 8). After adjusting for confounders, only less education, intravenous antibiotics, psychiatric medications and psychotherapy were significantly associated with elevated psychological symptoms. Specifically, regardless of lung function, patients who were depressed or anxious reported worse HRQoL. Conclusions: The prevalence of elevated symptoms of depression and anxiety was high in Spanish adult patients with CF, and these symptoms were associated with a decreased HRQoL.
| Original language | English (US) |
|---|---|
| Journal | General Hospital Psychiatry |
| DOIs | |
| State | Accepted/In press - Jul 23 2015 |
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Keywords
- Anxiety
- Cystic fibrosis
- Depression
- Lung function
- Quality of life
ASJC Scopus subject areas
- Psychiatry and Mental health
Cite this
Depression and anxiety symptoms in Spanish adult patients with cystic fibrosis : Associations with health-related quality of life. / Olveira, C.; Sole, A.; Girón, R. M.; Quintana-Gallego, E.; Mondejar, P.; Baranda, F.; Alvarez, A.; Prados, C.; Rodríguez-González, J.; Herrero-Labarga, I.; Quittner, Alexandra; Olveira, G.
In: General Hospital Psychiatry, 23.07.2015.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Depression and anxiety symptoms in Spanish adult patients with cystic fibrosis
T2 - Associations with health-related quality of life
AU - Olveira, C.
AU - Sole, A.
AU - Girón, R. M.
AU - Quintana-Gallego, E.
AU - Mondejar, P.
AU - Baranda, F.
AU - Alvarez, A.
AU - Prados, C.
AU - Rodríguez-González, J.
AU - Herrero-Labarga, I.
AU - Quittner, Alexandra
AU - Olveira, G.
PY - 2015/7/23
Y1 - 2015/7/23
N2 - Background: Cystic fibrosis (CF) is a chronic disease with an impact on the quality of life. Self-reported symptoms of depression and anxiety were assessed in the Spanish cohort of the International Epidemiological Study on Depression and Anxiety in patients with CF (International Depression-Anxiety Epidemiological Study) and their relationship with health status and health-related quality of life (HRQoL) was evaluated. Methods: This cross-sectional study recruited adult patients with CF at 10 Spanish centers. Patients completed the Hospital Anxiety and Depression Scale (HADS) and the Revised Cystic Fibrosis Questionnaire. Demographic and health data were recorded from medical charts. Logistic regression was used to determine the predictors of elevated symptoms of depression and anxiety (HADS. ≥. 8). Results: Of the 336 participants recruited (mean age, 28.1. years; 48.2% women), 41 (12.2%) had elevated depression-related scores, and 100 (29.7%) had elevated anxiety-related scores (HADS. ≥. 8). After adjusting for confounders, only less education, intravenous antibiotics, psychiatric medications and psychotherapy were significantly associated with elevated psychological symptoms. Specifically, regardless of lung function, patients who were depressed or anxious reported worse HRQoL. Conclusions: The prevalence of elevated symptoms of depression and anxiety was high in Spanish adult patients with CF, and these symptoms were associated with a decreased HRQoL.
AB - Background: Cystic fibrosis (CF) is a chronic disease with an impact on the quality of life. Self-reported symptoms of depression and anxiety were assessed in the Spanish cohort of the International Epidemiological Study on Depression and Anxiety in patients with CF (International Depression-Anxiety Epidemiological Study) and their relationship with health status and health-related quality of life (HRQoL) was evaluated. Methods: This cross-sectional study recruited adult patients with CF at 10 Spanish centers. Patients completed the Hospital Anxiety and Depression Scale (HADS) and the Revised Cystic Fibrosis Questionnaire. Demographic and health data were recorded from medical charts. Logistic regression was used to determine the predictors of elevated symptoms of depression and anxiety (HADS. ≥. 8). Results: Of the 336 participants recruited (mean age, 28.1. years; 48.2% women), 41 (12.2%) had elevated depression-related scores, and 100 (29.7%) had elevated anxiety-related scores (HADS. ≥. 8). After adjusting for confounders, only less education, intravenous antibiotics, psychiatric medications and psychotherapy were significantly associated with elevated psychological symptoms. Specifically, regardless of lung function, patients who were depressed or anxious reported worse HRQoL. Conclusions: The prevalence of elevated symptoms of depression and anxiety was high in Spanish adult patients with CF, and these symptoms were associated with a decreased HRQoL.
KW - Anxiety
KW - Cystic fibrosis
KW - Depression
KW - Lung function
KW - Quality of life
UR - http://www.scopus.com/inward/record.url?scp=84959916327&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84959916327&partnerID=8YFLogxK
U2 - 10.1016/j.genhosppsych.2016.02.002
DO - 10.1016/j.genhosppsych.2016.02.002
M3 - Article
C2 - 26971246
AN - SCOPUS:84959916327
JO - General Hospital Psychiatry
JF - General Hospital Psychiatry
SN - 0163-8343
ER -