Dental Implants and the Use of rhBMP-2

Daniel B. Spagnoli, Robert E. Marx

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations


Tissue engineering is an emerging field of medicine and dentistry that combines the body's natural biologic response to tissue injury with engineering principles. The goal is to replicate or reconstruct the natural form and function of missing tissues and organs. Tissue-engineered bone with native qualities will be necessary for implantation or migration of engineered teeth in the future, and is currently required for the osseointegration of dental implants. This article addresses the role of bone morphogenetic proteins (BMP) in native bone healing for implant osseointegration and the application of BMP for de novo bone regeneration.

Original languageEnglish (US)
Pages (from-to)347-361
Number of pages15
JournalOral and Maxillofacial Surgery Clinics of North America
Issue number2
StatePublished - May 2011


  • Bone morphogenetic proteins
  • De-novo bone regeneration
  • Dental implant
  • RhBMP-2
  • Tissue engineering

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology
  • Oral Surgery


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